Technology Process of C60H110N4O12
There total 4 articles about C60H110N4O12 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(1R,3R,4R,5R)-(-)-quinic acid tetraacetate;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane; N,N-dimethyl-formamide;
for 0.5h;
Inert atmosphere;
Cooling with ice;
[5-amino-5-(2-dihexadecylamino-ethylcarbamoyl)-pentyl]-carbamic acid tert-butyl ester;
In
dichloromethane; N,N-dimethyl-formamide;
at 25 ℃;
for 12h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane; N,N-dimethyl-formamide / 0.5 h / Inert atmosphere; Cooling with ice
1.2: 12 h / 25 °C
2.1: hydrogenchloride; hydrogen / 10 wt% Pd(OH)2 on carbon / water; methanol / 14 h / 25 °C / 1520.1 Torr
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane; N,N-dimethyl-formamide / 0.5 h / Inert atmosphere; Cooling with ice
3.2: 12 h / 25 °C
With
hydrogenchloride; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
10 wt% Pd(OH)2 on carbon;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane; N,N-dimethyl-formamide / 0.5 h / Inert atmosphere; Cooling with ice
1.2: 12 h / 25 °C
2.1: hydrogenchloride; hydrogen / 10 wt% Pd(OH)2 on carbon / water; methanol / 14 h / 25 °C / 1520.1 Torr
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane; N,N-dimethyl-formamide / 0.5 h / Inert atmosphere; Cooling with ice
3.2: 12 h / 25 °C
With
hydrogenchloride; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
10 wt% Pd(OH)2 on carbon;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;