N-(1-phenylpropyl)aniline

Base Information

• Chemical Name: N-(1-phenylpropyl)aniline
• CAS No.: 22920-59-8
• Molecular Formula: C15H17 N
• Molecular Weight: 211.307
• Hs Code.: 2921420090
• DSSTox Substance ID: DTXSID10446071
• Nikkaji Number: J678.651K
• Mol file: 22920-59-8.mol

Synonyms:N-(1-phenylpropyl)aniline;22920-59-8;PHENYL-(1-PHENYL-PROPYL)-AMINE;N-(alpha-Ethylbenzyl)aniline;SCHEMBL2507116;DTXSID10446071;AKOS000223199;AKOS022172834;SB78785

Chemical Property of N-(1-phenylpropyl)aniline

Chemical Property:

• PSA: 12.03000
• LogP: 4.32280
• Storage Temp.: 2-8°C
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 211.136099547
• Heavy Atom Count: 16
• Complexity: 178

Purity/Quality:

99% ^*data from raw suppliers

PHENYL-(1-PHENYL-PROPYL)-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C1=CC=CC=C1)NC2=CC=CC=C2

Technology Process of N-(1-phenylpropyl)aniline

There total 33 articles about N-(1-phenylpropyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(E)-[1-phenylpropylidene]phenylamine (67888-69-1) → N-(1-phenylpropyl)aniline (22920-59-8)

Guidance literature:

With 1,5-dimethylcyclohexa-1,4-diene; tris(pentafluorophenyl)borate; In toluene; at 125 ℃; for 18h; Glovebox; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.201409246

Reference yield: 99.0%

aniline (62-53-3) + 1-phenyl-propan-1-one (93-55-0) → N-(1-phenylpropyl)aniline (22920-59-8)

Guidance literature:

With 1-hydrosilatrane; acetic acid; Sealed tube;

DOI:10.1021/acs.joc.8b03073

Reference yield: 97.0%

1,N-Diphenylpropanimine (14752-72-8) → N-(1-phenylpropyl)aniline (22920-59-8)

Guidance literature:

With isopropyl alcohol; [Ru2(CO)4(μ-H)(C4Ph4COHOCC4Ph4)]; In benzene; at 70 ℃; for 1h;

DOI:10.1002/1521-3765(20020703)8:13<2955::AID-CHEM2955>3.0.CO;2-Q

upstream raw materials:

1-phenyl-1-(phenylamino)propan-2-one

ethylmagnesium iodide

benzylidene phenylamine

ethylmagnesium bromide

Downstream raw materials:

1,N-Diphenylpropanimine

N-(α-ethylbenzyl)-N-methylaniline

Refernces

• 1、 Wang, Qing,Ni, Shengyang,Wang, Xiaochen,Wang, Yi,Pan, Yi. "Visible-light-mediated tungsten-catalyzed C-H amination of unactivated alkanes with nitroarenes". . p. 678 - 685. Retrieved 2022/02/14.
• 2、 Agbossou-Niedercorn, Francine,Corre, Yann,Dongare, Mohan K.,Kemnitz, Erhard,Kokane, Reshma,Michon, Christophe,Umbarkar, Shubhangi B.. "Palladium supported on magnesium hydroxyl fluoride: An effective acid catalyst for the hydrogenation of imines and N-heterocycles". supporting information. p. 19572 - 19583. Retrieved 2021/11/04.