2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester

Base Information

• Chemical Name: 2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester
• CAS No.: 852820-66-7
• Molecular Formula: C₁₈H₂₈O₄Si
• Molecular Weight: 336.503

Synonyms:2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester

Chemical Property of 2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester

There total 3 articles about 2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl-2,3-dihydroxybenzoate (2411-83-8) → 2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester (852820-66-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / N,N-diisopropylethylamine / dimethylformamide / 0.33 h / 0 °C

2: 63 percent / DEAD; PPh₃ / tetrahydrofuran / 3 h / 23 °C

With N-ethyl-N,N-diisopropylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; N,N-dimethyl-formamide; 2: Mitsunobu reaction;

DOI:10.1021/jm050019i

Reference yield:

2,3-Dihydroxybenzoic acid (303-38-8) → 2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester (852820-66-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: aq. Cs₂CO₃ / methanol / 0.5 h / 23 °C

1.2: 81 percent / dimethylformamide / 13 h / 23 °C

2.1: 96 percent / N,N-diisopropylethylamine / dimethylformamide / 0.33 h / 0 °C

3.1: 63 percent / DEAD; PPh₃ / tetrahydrofuran / 3 h / 23 °C

With caesium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; 3.1: Mitsunobu reaction;

DOI:10.1021/jm050019i

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → 2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester (852820-66-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / N,N-diisopropylethylamine / dimethylformamide / 0.33 h / 0 °C

2: 63 percent / DEAD; PPh₃ / tetrahydrofuran / 3 h / 23 °C

With N-ethyl-N,N-diisopropylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; N,N-dimethyl-formamide; 2: Mitsunobu reaction;

DOI:10.1021/jm050019i

upstream raw materials:

methyl-2,3-dihydroxybenzoate

2,3-Dihydroxybenzoic acid

tert-butyldimethylsilyl chloride

Downstream raw materials:

N-((S)-1-{(R)-2-[(Benzo[1,3]dioxole-5-sulfonyl)-isobutyl-amino]-1-hydroxy-ethyl}-hept-6-enyl)-2-but-3-enyloxy-3-hydroxy-benzamide

(1''S,1'''R)-2-but-3'-enyloxy-3-hydroxy-N-(1''-{1'''-hydroxy-2'''-[isobutyl-(4-methoxybenzenesulfonyl)amino]ethyl}hex-5''-enyl)benzamide

2-(but-3-enyloxy)-3-hydroxybenzoic acid

2-but-3-enyloxy-3-hydroxy-benzoic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 852820-66-7 2-but-3-enyloxy-3-(tert-butyldimethylsilanyloxy)benzoic acid methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send