2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid

Base Information

Chemical Name:2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid
CAS No.:1034383-96-4
Molecular Formula:C₁₇H₂₀N₂O₄
Molecular Weight:316.357
Hs Code.:

Synonyms:2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid

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Chemical Property of 2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid

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Technology Process of 2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid

There total 4 articles about 2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 89890-32-4
N-{2-(salicylideneamino)ethyl}-(o-hydroxyphenyl)glycine

: 1034383-96-4
2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 6h; under 2068.65 Torr;
DOI:10.1021/jf100994s

Reference yield: 80.0%

: 1034383-96-4
2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid

Guidance literature:

Reference yield:

: 1234513-25-7
C₁₂H₁₆N₂O₄

: 1034383-96-4
2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride; water / 2 h / Reflux

2.1: sodium hydrogencarbonate / water / pH 7.2

2.2: 1 h / 20 °C

3.1: palladium 10% on activated carbon; hydrogen / methanol / 6 h / 20 °C / 2068.65 Torr

With hydrogenchloride; palladium 10% on activated carbon; water; hydrogen; sodium hydrogencarbonate; In methanol; water;
DOI:10.1021/jf100994s