methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate

Base Information

• Chemical Name: methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate
• CAS No.: 494838-63-0
• Molecular Formula: C₂₁H₃₂N₂O₄S
• Molecular Weight: 408.562

Synonyms:methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate

Chemical Property of methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate

There total 2 articles about methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

benzyl bromide (100-39-0) + methyl (S)-2-((S)-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate (494838-62-9) → methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate (494838-63-0)

Guidance literature:

With potassium carbonate; In acetonitrile; at 70 ℃; for 96h;

DOI:10.1021/ol027074v

Reference yield:

(S)-2-((Z)-(S)-4-Amino-5-methyl-hex-2-enylamino)-4-methyl-pentanoic acid methyl ester (384824-25-3) → methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate (494838-63-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / sulfamide / pyridine / 12 h / Heating

2: 92 percent / K₂CO₃ / acetonitrile / 96 h / 70 °C

With potassium carbonate; SULFAMIDE; In pyridine; acetonitrile;

DOI:10.1021/ol027074v

Reference yield: 77.0%

methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate (494838-63-0) → (S)-2-((4R,5S,6S)-7-Benzyl-4,5-dihydroxy-6-isopropyl-1,1-dioxo-1λ6-[1,2,7]thiadiazepan-2-yl)-4-methyl-pentanoic acid methyl ester + (S)-2-((4S,5R,6S)-7-Benzyl-4,5-dihydroxy-6-isopropyl-1,1-dioxo-1λ6-[1,2,7]thiadiazepan-2-yl)-4-methyl-pentanoic acid methyl ester

Guidance literature:

With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In water; acetone; at 20 ℃;

DOI:10.1021/ol027074v

upstream raw materials:

benzyl bromide

methyl (S)-2-((S)-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate

(S)-2-((Z)-(S)-4-Amino-5-methyl-hex-2-enylamino)-4-methyl-pentanoic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 494838-63-0 methyl (S)-2-((S)-7-benzyl-6-isopropyl-1,1-dioxido-6,7-dihydro-1,2,7-thiadiazepin-2(3H)-yl)-4-methylpentanoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send