Technology Process of (1α,2β,3α,4β,6β)-4,6-Diamino-1,2,3-cyclohexantriol
There total 46 articles about (1α,2β,3α,4β,6β)-4,6-Diamino-1,2,3-cyclohexantriol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
methanol; water;
for 3h;
DOI:10.1021/jo049788k
- Guidance literature:
-
With
hydrogenchloride;
In
methanol;
DOI:10.1139/v87-246
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 85 percent / DIPEA; DMAP / CH2Cl2 / 5 h / 20 °C
2: 85 percent / NaN3; NH4Cl / methanol / 40 h / Heating
3: 72 percent / m-chloroperbenzoic acid / CH2Cl2 / 20 °C
4: 82 percent / Yb(OTf)3; Et3N; NaN3 / molecular sieves 4 Angstroem / toluene / 96 h / 80 °C
5: 100 percent / HCl / methanol / 20 °C
6: 95 percent / H2 / Pd/C / methanol / 14 h / 2250.18 Torr
7: 96 percent / Et3N / methanol; H2O / 3 h
With
hydrogenchloride; dmap; sodium azide; hydrogen; ammonium chloride; triethylamine; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; ytterbium(III) triflate;
palladium on activated charcoal; 4 A molecular sieve;
In
methanol; dichloromethane; water; toluene;
DOI:10.1021/jo049788k
