1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol

Base Information

• Chemical Name: 1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol
• CAS No.: 107485-06-3
• Molecular Formula: C₁₉H₂₄O₂
• Molecular Weight: 284.398
• Mol file: 107485-06-3.mol

Synonyms:1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol

Chemical Property of 1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol

There total 3 articles about 1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-bis(m-acetylphenyl)propane (107485-14-3) → 1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol (107485-06-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Yield given;

DOI:10.1246/bcsj.59.2035

Reference yield:

1,3-bis(m-acetylphenyl)propane bis(ethylene acetal) (107484-99-1) → 1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol (107485-06-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 10 percent aq. HCl / dioxane / Ambient temperature

2: LiAlH₄ / diethyl ether

With hydrogenchloride; lithium aluminium tetrahydride; In 1,4-dioxane; diethyl ether;

DOI:10.1246/bcsj.59.2035

Reference yield:

(4-(2-methyl-1,3-dioxolan-2-yl)phenyl)magnesium bromide (39575-67-2) + m-(3-bromopropyl)acetophenone ethylene acetal (107484-95-7) → 1-(3-{3-[3-(1-Hydroxy-ethyl)-phenyl]-propyl}-phenyl)-ethanol (107485-06-3)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo00384a005

upstream raw materials:

(4-(2-methyl-1,3-dioxolan-2-yl)phenyl)magnesium bromide

m-(3-bromopropyl)acetophenone ethylene acetal

1,3-bis(m-acetylphenyl)propane

1,3-bis(m-acetylphenyl)propane bis(ethylene acetal)

Downstream raw materials:

1-(m-vinylphenyl)-3-(p-vinylphenyl)propane