(5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside

Base Information

Chemical Name:(5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside
CAS No.:1382060-17-4
Molecular Formula:C₁₆H₂₂N₄O₅
Molecular Weight:350.374
Hs Code.:

Synonyms:(5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside

Suppliers and Price of (5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside

There total 5 articles about (5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1382060-16-3
benzyl 2,3,4-tri-O-methyl-α-D-mannopyranosidurononitrile

: 1382060-17-4
(5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside

Guidance literature:: With trimethylsilylazide; di(n-butyl)tin oxide; In toluene; at 120 ℃; for 16h;
DOI:10.1021/ol3013638

Reference yield:

: 1382060-13-0
benzyl 6-O-(tert-butyldimethyl)silyl-2,3,4-tri-O-methyl-α-D-mannopyranoside

: 1382060-17-4
(5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 6 h / 0 - 20 °C / Inert atmosphere

2: Dess-Martin periodane / dichloromethane / 2 h / 20 °C

3: pyridine; hydroxylamine hydrochloride / methanol; water / 2 h / 20 °C

4: pyridine; methanesulfonyl chloride / 2 h / 0 - 20 °C / Inert atmosphere

5: trimethylsilylazide; di(n-butyl)tin oxide / toluene / 16 h / 120 °C

With pyridine; trimethylsilylazide; hydroxylamine hydrochloride; tetrabutyl ammonium fluoride; di(n-butyl)tin oxide; Dess-Martin periodane; methanesulfonyl chloride; In tetrahydrofuran; methanol; dichloromethane; water; toluene;
DOI:10.1021/ol3013638

Reference yield:

: 1382060-15-2
benzyl 2,3,4-tri-O-methyl-α-D-mannopyranoside

: 1382060-17-4
(5R)-benzyl 2,3,4-tri-O-methyl-5-C-(1H-tetrazol-5-yl)-α-D-lyxopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: Dess-Martin periodane / dichloromethane / 2 h / 20 °C

2: pyridine; hydroxylamine hydrochloride / methanol; water / 2 h / 20 °C

3: pyridine; methanesulfonyl chloride / 2 h / 0 - 20 °C / Inert atmosphere

4: trimethylsilylazide; di(n-butyl)tin oxide / toluene / 16 h / 120 °C

With pyridine; trimethylsilylazide; hydroxylamine hydrochloride; di(n-butyl)tin oxide; Dess-Martin periodane; methanesulfonyl chloride; In methanol; dichloromethane; water; toluene;
DOI:10.1021/ol3013638