(3aR,6R,6aR)-6-(hydroxymethyl)spiro[6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-2,1'-cyclohexane]-4-one

Base Information

Chemical Name:(3aR,6R,6aR)-6-(hydroxymethyl)spiro[6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-2,1'-cyclohexane]-4-one
CAS No.:27304-20-7
Molecular Formula:C11H16 O5
Molecular Weight:246.25702
Hs Code.:
DSSTox Substance ID:DTXSID30559556
Nikkaji Number:J418.506D
Wikidata:Q82442307
Mol file:27304-20-7.mol

Synonyms:27304-20-7;(3aR,6R,6aR)-6-(hydroxymethyl)spiro[6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-2,1'-cyclohexane]-4-one;2,3-Cyclohexylidene-D-ribonic acid gamma-lactone;SCHEMBL7148032;DTXSID30559556;AKOS015912597;2 3-O-CYCLOHEXYLIDENE-D-RIBONIC ACID;2,3-Cyclohexylidene-D-ribonic acid gamma -lactone;J-016723;2,3-Cyclohexylidene-D-ribonic acid gamma-lactone, 97%;(3A'R,4'R,6a'R)-4'-(hydroxymethyl)dihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-6'(4'H)-one;(3a'R,6'R,6a'R)-6'-(Hydroxymethyl)dihydrospiro[cyclohexane-1,2'-furo[3,4-d][1,3]dioxol]-4'(3a'H)-one (non-preferred name);(3aR, 6R, 6aR)-6-(hydroxymethyl)spiro[6, 6a-dihydro-3aH-furo[3, 4-d][1, 3]dioxole-2, 1'-cyclohexane]-4-one

Suppliers and Price of (3aR,6R,6aR)-6-(hydroxymethyl)spiro[6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-2,1'-cyclohexane]-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
D-Ribonolactone 2,3-Cyclohexyl Ketal
250mg
$ 446.00

Usbiological
D-Ribonolactone 2,3-cyclohexyl ketal
100mg
$ 406.00

TRC
D-Ribonolactone2,3-CyclohexylKetal
1 g
$ 185.00

Sigma-Aldrich
2,3-Cyclohexylidene-D-ribonic acid γ-lactone 97%
1g
$ 198.00

Biosynth Carbosynth
D-Ribonolactone 2,3-cyclohexyl ketal
500 mg
$ 370.00

Biosynth Carbosynth
D-Ribonolactone 2,3-cyclohexyl ketal
250 mg
$ 202.50

Biosynth Carbosynth
D-Ribonolactone 2,3-cyclohexyl ketal
100 mg
$ 112.00

Biosynth Carbosynth
D-Ribonolactone 2,3-cyclohexyl ketal
2 g
$ 1223.10

Biosynth Carbosynth
D-Ribonolactone 2,3-cyclohexyl ketal
1 g
$ 672.70

American Custom Chemicals Corporation
2,3-CYCLOHEXYLIDENE-D-RIBONIC ACID GAMMA-LACTONE 95.00%
5MG
$ 502.74

Total 4 raw suppliers

Chemical Property of (3aR,6R,6aR)-6-(hydroxymethyl)spiro[6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-2,1'-cyclohexane]-4-one

Chemical Property:

Melting Point:130-133 °C(lit.)
Boiling Point:424.5±40.0 °C(Predicted)
PKA:13.68±0.10(Predicted)
PSA：64.99000
Density:1.34±0.1 g/cm3(Predicted)
LogP:0.34850
Solubility.:Chloroform, Dichloromethane,
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:228.09977361
Heavy Atom Count:16
Complexity:297

Purity/Quality:

97% ^*data from raw suppliers

D-Ribonolactone 2,3-Cyclohexyl Ketal ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2(CC1)OC3C(OC(=O)C3O2)CO
Isomeric SMILES:C1CCC2(CC1)O[C@@H]3[C@H](OC(=O)[C@@H]3O2)CO
Uses Protected D-Ribonolactone.

Technology Process of (3aR,6R,6aR)-6-(hydroxymethyl)spiro[6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-2,1'-cyclohexane]-4-one

There total 16 articles about (3aR,6R,6aR)-6-(hydroxymethyl)spiro[6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-2,1'-cyclohexane]-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: C₂₀H₂₈O₆

: 27304-20-7,546141-19-9
2,3-O-cyclohexylidene-γ-D-ribonolactone

Guidance literature:: C₂₀H₂₈O₆; With dipyridinium dichromate; acetic anhydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

With palladium 10% on activated carbon; hydrogen; In ethyl acetate; for 16h;
DOI:10.1016/j.tetlet.2014.02.082