Technology Process of 2-benzyl-6-methyl-4-phenylpyridine
There total 8 articles about 2-benzyl-6-methyl-4-phenylpyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trans-bis(triphenylphosphine)palladium dichloride; potassium carbonate;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 4h;
Schlenk technique;
Inert atmosphere;
DOI:10.1055/s-0033-1338548
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
2.1: trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / 1,2-dichloro-ethane / 72 h / 90 °C / Sealed tube; Inert atmosphere
2.2: 20 °C / Inert atmosphere
3.1: potassium carbonate; trans-bis(triphenylphosphine)palladium dichloride / N,N-dimethyl-formamide / 4 h / 80 °C / Schlenk technique; Inert atmosphere
With
trans-bis(triphenylphosphine)palladium dichloride; trimethylsilyl trifluoromethanesulfonate; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
3.1: |Suzuki-Miyaura Coupling;
DOI:10.1055/s-0033-1338548
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: ammonia / Inert atmosphere
2.1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
3.1: trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / 1,2-dichloro-ethane / 72 h / 90 °C / Sealed tube; Inert atmosphere
3.2: 20 °C / Inert atmosphere
4.1: potassium carbonate; trans-bis(triphenylphosphine)palladium dichloride / N,N-dimethyl-formamide / 4 h / 80 °C / Schlenk technique; Inert atmosphere
With
trans-bis(triphenylphosphine)palladium dichloride; trimethylsilyl trifluoromethanesulfonate; ammonia; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
4.1: |Suzuki-Miyaura Coupling;
DOI:10.1055/s-0033-1338548
