2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde

Base Information

Chemical Name:2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde
CAS No.:22383-86-4
Molecular Formula:C10H12 O4
Molecular Weight:196.203
Hs Code.:2912499000
DSSTox Substance ID:DTXSID60468400
Nikkaji Number:J2.229.585C
Wikidata:Q82295577
Mol file:22383-86-4.mol

Synonyms:2-HYDROXY-3,4-DIMETHOXY-6-METHYLBENZALDEHYDE;22383-86-4;Benzaldehyde,2-hydroxy-3,4-dimethoxy-6-methyl-;SCHEMBL12841729;DTXSID60468400;AKOS006228535;FT-0706062;2-hydroxy-3,4-dimethoxy-6-methylbenzaldehyde, AldrichCPR

Suppliers and Price of 2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde
2.5g
$ 175.00

TRC
2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde
500mg
$ 60.00

Total 5 raw suppliers

Chemical Property of 2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:110 °C
Refractive Index:1.561
Boiling Point:314.1°Cat760mmHg
PKA:7.91±0.20(Predicted)
Flash Point:121.9°C
PSA：55.76000
Density:1.197g/cm³
LogP:1.53030
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:196.07355886
Heavy Atom Count:14
Complexity:195

Purity/Quality:

99% ^*data from raw suppliers

2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1C=O)O)OC)OC

Technology Process of 2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde

There total 4 articles about 2-Hydroxy-3,4-dimethoxy-6-methylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 22383-85-3
2,3,4-trimethoxy-6-methylbenzaldehyde

: 22383-86-4
2-hydroxy-3,4-dimethoxy-6-methylbenzaldehyde

Guidance literature:: With boron tribromide; In dichloromethane; at -78 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jacs.6b06899

Reference yield:

: 6443-69-2
3,4,5-trimethoxytoluene

: 22383-86-4
2-hydroxy-3,4-dimethoxy-6-methylbenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 82.7 percent / POCl₃ / 1 h / 90 °C

2: 78.3 percent / BCl₃ / CH₂Cl₂ / 2.5 h / -78 °C

With boron trichloride; trichlorophosphate; In dichloromethane;
DOI:10.1248/cpb.40.2614

Reference yield:

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 22383-86-4
2-hydroxy-3,4-dimethoxy-6-methylbenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: N₂H₄*H₂O, KOH, triethylene glycol

2: POCl₃

3: AlCl₃

With potassium hydroxide; aluminium trichloride; hydrazine hydrate; trichlorophosphate; 2,2'-[1,2-ethanediylbis(oxy)]bisethanol;