5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose

Base Information

Chemical Name:5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose
CAS No.:1233484-17-7
Molecular Formula:C₃₀H₃₆O₅Si
Molecular Weight:504.698
Hs Code.:

Synonyms:5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose

Suppliers and Price of 5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose

There total 9 articles about 5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 58479-61-1
tert-butylchlorodiphenylsilane

: 18439-35-5
(3aR,5R,6S,6aR)-5-((R)-hydroxy(phenyl)methyl)-2,2-dimethyl-tetrahydrofuro[2,3-d][1,3]dioxole-6-ol

: 1233484-17-7
5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose

Guidance literature:: With 1H-imidazole; In dichloromethane; at 20 ℃; for 48h;
DOI:10.1016/j.tetlet.2010.04.114

Reference yield:

: 18685-18-2
3-O-benzyl-1,2-5,6-O-diisopropylidene-α-D-glucofuranose

: 1233484-17-7
5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose

Guidance literature:: Multi-step reaction with 4 steps

1: periodic acid / ethyl acetate / 24 h / 20 °C

2: tetrahydrofuran; toluene / 24 h / 0 - 20 °C / Inert atmosphere

3: hydrogen; palladium 10% on activated carbon / methanol / 23 h / 20 °C / 760.05 Torr

4: 1H-imidazole / dichloromethane / 48 h / 20 °C

With 1H-imidazole; palladium 10% on activated carbon; hydrogen; periodic acid; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate; toluene; 2: |Grignard Reaction;
DOI:10.1016/j.tet.2015.05.040

Reference yield:

: 65462-15-9
3-O-benzyl-1,2-O-isopropylidene-β-L-arabino-pentodialdo-1,4-furanose

: 1233484-17-7
5-O-(tert-butyldiphenylsilyl)-1,2-O-isopropylidene-5-C-phenyl-α-D-gluco-pentofuranose

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; toluene / 24 h / 0 - 20 °C / Inert atmosphere

2: hydrogen; palladium 10% on activated carbon / methanol / 23 h / 20 °C / 760.05 Torr

3: 1H-imidazole / dichloromethane / 48 h / 20 °C

With 1H-imidazole; palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol; dichloromethane; toluene; 1: |Grignard Reaction;
DOI:10.1016/j.tet.2015.05.040