(2-Hydroxypyridin-3-yl)(phenyl)methanone

Base Information

Chemical Name:(2-Hydroxypyridin-3-yl)(phenyl)methanone
CAS No.:27039-12-9
Molecular Formula:C12H9 N O2
Molecular Weight:199.21
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50355810
Wikidata:Q82134862
Mol file:27039-12-9.mol

Synonyms:27039-12-9;(2-hydroxypyridin-3-yl)(phenyl)methanone;(2-Hydroxy-pyridin-3-yl)-phenyl-methanone;3-benzoyl-1H-pyridin-2-one;(2-Hydroxy-[3]-pyridyl)-phenyl ketone;3-benzoyl-1,2-dihydropyridin-2-one;3-benzoylpyridin-2-ol;3-benzoylhydroxypyridine;SCHEMBL13278446;DTXSID50355810;CBA03912;MFCD00234779;AKOS006274719;SB36310;AC-14994;CS-0342915;FT-0690296;(2-HYDROXY-[3]-PYRIDYL)-PHENYLKETONE;J-016655

Suppliers and Price of (2-Hydroxypyridin-3-yl)(phenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-benzoyl-1H-pyridin-2-one
100mg
$ 200.00

J&W Pharmlab
(2-Hydroxy-pyridin-3-yl)-phenyl-methanone 96%
5g
$ 1560.00

J&W Pharmlab
(2-Hydroxy-pyridin-3-yl)-phenyl-methanone 96%
500mg
$ 249.00

J&W Pharmlab
(2-Hydroxy-pyridin-3-yl)-phenyl-methanone 96%
1g
$ 398.00

Crysdot
(2-Hydroxypyridin-3-yl)(phenyl)methanone 95+%
1g
$ 356.00

Chemenu
(2-hydroxypyridin-3-yl)(phenyl)methanone 95%
1g
$ 337.00

American Custom Chemicals Corporation
(2-HYDROXY-[3]-PYRIDYL)-PHENYL KETONE 95.00%
100MG
$ 885.31

Alichem
(2-Hydroxypyridin-3-yl)(phenyl)methanone
1g
$ 400.00

Total 8 raw suppliers

Chemical Property of (2-Hydroxypyridin-3-yl)(phenyl)methanone

Chemical Property:

Vapor Pressure:1.48E-07mmHg at 25°C
Refractive Index:1.606
Boiling Point:428.7°C at 760 mmHg
Flash Point:192.5°C
PSA：50.19000
Density:1.24g/cm³
LogP:2.01820
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:199.063328530
Heavy Atom Count:15
Complexity:336

Purity/Quality:

97% ^*data from raw suppliers

3-benzoyl-1H-pyridin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=CC=CNC2=O

Technology Process of (2-Hydroxypyridin-3-yl)(phenyl)methanone

There total 7 articles about (2-Hydroxypyridin-3-yl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: N-Benzyl-N-((2S,4S)-5-cyano-2-ethoxy-6-phenyl-3,4-dihydro-2H-pyran-4-yl)-acetamide

: 27039-12-9
3-Benzoyl-1,2-dihydro-pyridin-2-one

Guidance literature:: With sulfuric acid; at 180 ℃; for 3h;
DOI:10.1007/BF00807063

Reference yield:

: 614-16-4
Benzoylacetonitrile

: 27039-12-9
3-Benzoyl-1,2-dihydro-pyridin-2-one

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / tetrahydrofuran / 2 h / Ambient temperature

2: 91.5 percent / CH₂Cl₂ / 1.5 h

3: 50 percent / 4-(N,N-dimethylamino)-pyridine, Et₃N / tetrahydrofuran; various solvent(s) / 1.) 70 deg C, 6 h, 2.) r.t., overnight

4: hydroquinone / toluene / 48 h / 100 - 120 °C

5: 74 percent / 75percent H₂SO₄ / 3 h / 180 °C

With dmap; sulfuric acid; triethylamine; hydroquinone; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1007/BF00807063

Reference yield:

: 174652-94-9
1-phenyl-2-cyano-3-dimethylaminopropen-1-one

: 27039-12-9
3-Benzoyl-1,2-dihydro-pyridin-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: 91.5 percent / CH₂Cl₂ / 1.5 h

2: 50 percent / 4-(N,N-dimethylamino)-pyridine, Et₃N / tetrahydrofuran; various solvent(s) / 1.) 70 deg C, 6 h, 2.) r.t., overnight

3: hydroquinone / toluene / 48 h / 100 - 120 °C

4: 74 percent / 75percent H₂SO₄ / 3 h / 180 °C

With dmap; sulfuric acid; triethylamine; hydroquinone; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1007/BF00807063