3-Chloro-2',4'-dimethoxypropiophenone

Base Information

• Chemical Name: 3-Chloro-2',4'-dimethoxypropiophenone
• CAS No.: 22174-32-9
• Molecular Formula: C11H13 Cl O3
• Molecular Weight: 228.675
• Hs Code.: 2914700090
• Mol file: 22174-32-9.mol

Synonyms:Propiophenone,3-chloro-2',4'-dimethoxy- (8CI); 3-Chloro-1-(2,4-dimethoxyphenyl)propan-1-one

Chemical Property of 3-Chloro-2',4'-dimethoxypropiophenone

Chemical Property:

• PSA: 35.53000
• LogP: 2.51540

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Chloro-2',4'-dimethoxypropiophenone

There total 3 articles about 3-Chloro-2',4'-dimethoxypropiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-chloropropionyl chloride (625-36-5) + 1,3-Dimethoxybenzene (151-10-0) → 3-chloro-1-(2,4-dimethoxyphenyl)propan-1-one (22174-32-9)

Guidance literature:

1,3-Dimethoxybenzene; With aluminum (III) chloride; In dichloromethane; at 0 ℃; for 0.5h;

2-chloropropionyl chloride; In dichloromethane; at 0 ℃; for 6h;

DOI:10.1016/j.ejmech.2017.11.016

Reference yield:

chloropropionic acid (107-94-8) + 1,3-Dimethoxybenzene (151-10-0) → 3-chloro-1-(2,4-dimethoxyphenyl)propan-1-one (22174-32-9)

Guidance literature:

With aluminium trichloride; In carbon disulfide;

DOI:10.1139/v69-252

Reference yield:

→ 3-chloro-1-(2,4-dimethoxyphenyl)propan-1-one (22174-32-9)

Guidance literature:

1,3-Dimethoxybenzol;

upstream raw materials:

chloropropionic acid

1,3-Dimethoxybenzene

2-chloropropionyl chloride

Downstream raw materials:

2'.3.4'-Trimethoxy-propiophenon

2'.4'-Dimethoxy-3-ethoxy-propiophenon

1-(benzo-1,2,5-thiadiazol-5-ylmethylcarbonyl)-3-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazole