1-(Thiophen-2-yl)pent-4-en-1-one

Base Information

Chemical Name:1-(Thiophen-2-yl)pent-4-en-1-one
CAS No.:59304-44-8
Molecular Formula:C₉H₁₀OS
Molecular Weight:166.244
Hs Code.:
DSSTox Substance ID:DTXSID201308423

Synonyms:1-(thiophen-2-yl)pent-4-en-1-one;59304-44-8;1-thiophen-2-ylpent-4-en-1-one;4-Penten-1-one, 1-(2-thienyl)-;DTXSID201308423;1-(2-Thienyl)-4-penten-1-one;AKOS013637451;A934057

Suppliers and Price of 1-(Thiophen-2-yl)pent-4-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
1-(thiophen-2-yl)pent-4-en-1-one
5g
$ 1728.00

Rieke Metals
1-(thiophen-2-yl)pent-4-en-1-one
1g
$ 661.00

Total 1 raw suppliers

Chemical Property of 1-(Thiophen-2-yl)pent-4-en-1-one

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:166.04523611
Heavy Atom Count:11
Complexity:154

Purity/Quality:: 1-(thiophen-2-yl)pent-4-en-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=CCCC(=O)C1=CC=CS1

Technology Process of 1-(Thiophen-2-yl)pent-4-en-1-one

There total 13 articles about 1-(Thiophen-2-yl)pent-4-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1-(thiophen-2-yl)pent-4-en-1-one O-methyl oxime

: 59304-44-8
1-(thiophen-2-yl)pent-4-en-1-one

: 2-methyl-5-(thiophen-2-yl)-3,4-dihydro-2H-pyrrole

Guidance literature:: With samarium; iodine; In tetrahydrofuran; at 60 ℃; for 4h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.9b02740

Reference yield:

: 5162-44-7
1-bromo-4-butene

: 229970-94-9
N‐methoxy‐N‐methyl‐2‐thiophenecarboxamide

: 59304-44-8
1-(thiophen-2-yl)pent-4-en-1-one

Guidance literature:: 1-bromo-4-butene; With magnesium; In tetrahydrofuran; for 2h; Inert atmosphere; Reflux;

N‐methoxy‐N‐methyl‐2‐thiophenecarboxamide; In tetrahydrofuran; at -10 - 20 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.9b02740

Reference yield:

: 5271-67-0
2-Thiophenecarbonyl chloride

: 59304-44-8
1-(thiophen-2-yl)pent-4-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 12 h / 0 - 20 °C

2: triethylamine / tetrahydrofuran / 3 h / 0 - 20 °C

With triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.orglett.9b02230