4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene

Base Information

• Chemical Name: 4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene
• CAS No.: 943442-63-5
• Molecular Formula: C₁₆H₃₁NO₃Si
• Molecular Weight: 313.513
• Mol file: 943442-63-5.mol

Synonyms:4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene

Chemical Property of 4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene

There total 1 articles about 4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) + (1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine (194233-66-4) → 4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene (943442-63-5)

Guidance literature:

In toluene; at 20 ℃; for 72h;

DOI:10.1021/jm0609869

Reference yield:

acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) + 4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene (943442-63-5) → 3-[3-(2-methoxycarbonyl-ethyl)-6-oxo-cyclohex-1-enyl]-propionic acid methyl ester

Guidance literature:

4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene; With pyridine hydrogenfluoride; In acetonitrile; at -10 ℃; for 4h;

acrylic acid methyl ester; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 185 ℃; for 24h;

DOI:10.1021/jm0609869

Reference yield:

4-carbomethoxy-3-dimethylamino-1-tert-butyldimethylsiloxy-1-cyclohexene (943442-63-5) → methyl 4-oxocyclohex-1-ene-1-carboxylate (67201-29-0) + methyl 4-oxocyclohex-2-ene-1-carboxylate (67201-30-3)

Guidance literature:

With pyridine hydrogenfluoride; In acetonitrile; at -10 ℃; for 4h; Title compound not separated from byproducts;

DOI:10.1021/jm0609869

upstream raw materials:

acrylic acid methyl ester

(1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine

Downstream raw materials:

methyl 4-oxocyclohex-1-ene-1-carboxylate

methyl 4-oxocyclohex-2-ene-1-carboxylate

4-(hydroxymethyl)-2-cyclohexene-1-one