3-[tert-butyl(dimethyl)silyl]oxy-N,N-dimethylbuta-1,3-dien-1-amine

Base Information

• Chemical Name: 3-[tert-butyl(dimethyl)silyl]oxy-N,N-dimethylbuta-1,3-dien-1-amine
• CAS No.: 194233-66-4
• Molecular Formula: C12H25 N O Si
• Molecular Weight: 227.422
• DSSTox Substance ID: DTXSID50401644
• Mol file: 194233-66-4.mol

Synonyms:3-[tert-butyl(dimethyl)silyl]oxy-N,N-dimethylbuta-1,3-dien-1-amine;MFCD01863582;C12H25NOSi;DTXSID50401644;BCP32350;SY234397;FT-0774274;(1E)-3-[tert-butyl(dimethyl)silyl]oxy-N,N-dimethylbuta-1,3-dien-1-amine;[3-(Tert-Butyl-Dimethyl-SilanYl-Oxy)-Buta-1,3-Dienyl]-Dimethyl-Amine

Chemical Property of 3-[tert-butyl(dimethyl)silyl]oxy-N,N-dimethylbuta-1,3-dien-1-amine

Chemical Property:

• Vapor Pressure: 0.0429mmHg at 25°C
• Refractive Index: n20/D 1.493(lit.)
• Boiling Point: 234 °C(lit.)
• Flash Point: 200 °F
• PSA: 12.47000
• Density: 0.878 g/mL at 25 °C(lit.)
• LogP: 3.59720
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 227.170540955
• Heavy Atom Count: 15
• Complexity: 249

Purity/Quality:

97% ^*data from raw suppliers

(E)-3-((tert-Butyldimethylsilyl)oxy)-N,N-dimethylbuta-1,3-dien-1-amine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)OC(=C)C=CN(C)C

Technology Process of 3-[tert-butyl(dimethyl)silyl]oxy-N,N-dimethylbuta-1,3-dien-1-amine

There total 1 articles about 3-[tert-butyl(dimethyl)silyl]oxy-N,N-dimethylbuta-1,3-dien-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(E)-4-(dimethylamino)but-3-en-2-one (2802-08-6) + tert-butyldimethylsilyl chloride (18162-48-6) → (1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine (194233-66-4)

Guidance literature:

(E)-4-(dimethylamino)but-3-en-2-one; With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 - 0 ℃; for 1h;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; toluene; at -78 - 20 ℃;

Reference yield: 93.0%

4-Trifluoromethylbenzaldehyde (455-19-6) + (1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine (194233-66-4) → (E)-1-(dimethylamino)-5-(4-(trifluoromethyl)phenyl)-5-hydroxypent-1-en-3-one (1321936-89-3)

Guidance literature:

With water; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2011.06.035

Reference yield: 90.0%

phenylglyoxylic acid ethyl ester (1603-79-8) + (1E)-3-{[tert-butyl(dimethyl)silyl]oxy}-N,N-dimethyl-1,3-butadien-1-amine (194233-66-4) → (E)-ethyl 6-(dimethylamino)-2-hydroxy-4-oxo-2-phenylhex-5-enoate (1321937-25-0)

Guidance literature:

With water; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2011.06.035

upstream raw materials:

(E)-4-(dimethylamino)but-3-en-2-one

tert-butyldimethylsilyl chloride