2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol

Base Information

• Chemical Name: 2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol
• CAS No.: 1616860-66-2
• Molecular Formula: C₃₃H₅₀N₂O₃
• Molecular Weight: 522.772
• Mol file: 1616860-66-2.mol

Synonyms:2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol

Chemical Property of 2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol

There total 1 articles about 2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(1-aminomethyl-2-hydroxyethyl)amine (2811-20-3) + 3,5-di-tert-butyl-2-hydroxybenzaldehyde (37942-07-7) → 2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol (1616860-66-2)

Guidance literature:

In methanol; Reflux; Inert atmosphere;

DOI:10.1039/c4gc00709c

Reference yield: 95.0%

2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol (1616860-66-2) + methanesulfonyl chloride (124-63-0) → 2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propyl methanesulfonate (1616860-68-4)

Guidance literature:

With triethylamine; In dichloromethane; for 1h; Inert atmosphere;

DOI:10.1039/c4gc00709c

Reference yield:

2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propan-1-ol (1616860-66-2) → C42H66N4O4

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 1 h / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine; potassium iodide / acetonitrile / 24 h / Reflux; Inert atmosphere

With triethylamine; N-ethyl-N,N-diisopropylamine; potassium iodide; In dichloromethane; acetonitrile;

DOI:10.1039/c4gc00709c

upstream raw materials:

N-(1-aminomethyl-2-hydroxyethyl)amine

3,5-di-tert-butyl-2-hydroxybenzaldehyde

Downstream raw materials:

2,3-bis((E)-(3,5-di-tert-butyl-2-hydroxybenzylidene)amino)propyl methanesulfonate