ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate

Base Information

Chemical Name:ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate
CAS No.:1080521-47-6
Molecular Formula:C₂₇H₂₆Cl₂N₂O₆S
Molecular Weight:577.485
Hs Code.:

Synonyms:ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate

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Chemical Property of ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate

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Technology Process of ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate

There total 7 articles about ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1080521-45-4
ethyl 2-(4-(4-amino-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate

: 16271-33-3
2,4-Dichlorobenzenesulfonyl chloride

: 1080521-47-6
ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate

Guidance literature:: With pyridine; at 20 ℃;
DOI:10.1016/j.bmcl.2014.04.092

Reference yield:

: 1080521-35-2
2-(4-(4-amino-2-nitrophenoxy)-3-methoxyphenyl)acetic acid

: 1080521-47-6
ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate

Guidance literature:: Multi-step reaction with 5 steps

1: potassium tert-butylate / dimethyl sulfoxide / 20 °C

2: sulfuric acid

3: caesium carbonate / N,N-dimethyl-formamide / 20 °C

4: tin(ll) chloride / ethyl acetate / Reflux

5: pyridine / 20 °C

With pyridine; sulfuric acid; potassium tert-butylate; caesium carbonate; tin(ll) chloride; In dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2014.04.092

Reference yield:

: 1080521-36-3
2-(3-methoxy-4-(2-methyl-4-nitro-1H-indol-5-yloxy)phenyl)acetic acid

: 1080521-47-6
ethyl 2-(4-(4-(2,4-dichlorophenylsulfonamido)-1,2-dimethyl-1H-indol-5-yloxy)-3-methoxyphenyl)acetate

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid

2: caesium carbonate / N,N-dimethyl-formamide / 20 °C

3: tin(ll) chloride / ethyl acetate / Reflux

4: pyridine / 20 °C

With pyridine; sulfuric acid; caesium carbonate; tin(ll) chloride; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2014.04.092