16271-33-3

Basic information

• Product Name: 2,4-Dichlorobenzenesulfonyl chloride
• Synonyms: 2,4-dichloro-benzenesulfonylchlorid;2,4-DICHLOROBENZENE-1-SULFONYL CHLORIDE;2,4-DICHLOROBENZENESULFONYL CHLORIDE;2,4-DICHLOROBENZENESULPHONYL CHLORIDE;BUTTPARK 96\57-47;2,4-Dichlorobenzenesulphonyl chloride 98%;2,4-Dichlorobenzenesulfonic acid chloride;2,4-Dichlorobenzenesulfonyl chloride,98%
• CAS NO: 16271-33-3
• Molecular Formula: C₆H₃Cl₃O₂S
• Molecular Weight: 245.51
• EINECS: -0
• Product Categories: Benzenesulfonyl chloride;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
• Mol File: 16271-33-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 55-58 °C(lit.)
• Boiling Point: 114-115°C/0.1mm
• Flash Point: 140.3 °C
• Appearance: White to light beige/Crystalline Powder
• Density: 1.636 g/cm³
• Vapor Pressure: 0.00124mmHg at 25°C
• Refractive Index: 1.581
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• Sensitive: Moisture Sensitive
• Stability: Moisture Sensitive
• BRN: 2806192
• CAS DataBase Reference: 2,4-Dichlorobenzenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dichlorobenzenesulfonyl chloride(16271-33-3)
• EPA Substance Registry System: 2,4-Dichlorobenzenesulfonyl chloride(16271-33-3)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• RTECS: DB8927500
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 16271-33-3(Hazardous Substances Data)

Usage

Chemical Properties

white to light beige crystalline powder

Uses

2,4-Dichlorobenzenesulfonyl chloride may be used in the preparation of 2,4-dichlorothiophenol.

General Description

2,4-Dichlorobenzenesulfonyl chloride, also known as 2,4-dichlorophenylsulfonyl chloride, is an aryl sulfonyl chloride derivative. It participates in the synthesis of hexahydropyrazino[1,2-a]pyrimidine derivatives.

InChI:InChI=1/C6H3Cl3O2S/c7-4-1-2-6(5(8)3-4)12(9,10)11/h1-3H

Upstream product

• 7790-94-5 chlorosulfonic acid 
• 67-66-3 chloroform 
• 541-73-1 1,3-Dichlorobenzene 
• 7664-93-9 sulfuric acid 
• 554-00-7 2,4-Dichloroaniline 
• 609-62-1 2,4-dichloro-benzenesulfonic acid 

Downstream Products

• 21729-72-6 2,4-dichloro-1-(phenylsulfonyl)benzene 
• 180622-80-4 2,4-Dichloro-N-(4-hydroxy-butyl)-benzenesulfonamide 
• 909004-37-1 (3S)-1-(2,4-dichloro-benzenesulfonyl)-piperidine-3-carboxylic acid 
• 1380539-45-6 C₁₈H₁₈Cl₂F₃NO₃S 
• 1186643-76-4 9H-fluoren-9-ylmethyl ((1S)-1-{[(1S,4S)-5-({[(2,4-dichlorophenyl)sulfonyl]amino}acetyl)-2,5-diazabicyclo[2.2.1]hept-2-yl]carbonyl}-3-methylbutyl)carbamate 
• 1428330-60-2 4-[1-(2,4-dichlorobenzenesulfonyl)-4-hydroxypiperidin-4-ylmethoxy]benzonitrile 
• 1418119-49-9 (E)-ethyl 2-(2,4-dichlorobenzenesulfonyloxyimino)-2-phenylacetate 
• 1400667-89-1 2,4-dichloro-N-(5-(4-(tetrahydro-2H-pyran-4-yloxy)pyrido[3,2-d]pyrimidin-6-yl)pyridin-3-yl)benzenesulfonamide 
• 1392281-34-3 C₁₆H₁₃Cl₂N₃O₃S₂ 
• 33757-65-2 2,4-dichloro-N-(quinolin-8-yl)benzenesulfonamide 
• 1358577-95-3 N,N'-(6-(1,3-benzodioxol-5-yl)-1,3,5-triazine-2,4-diyl)-bis-2,4-dichlorobenzenesulfonamide 
• 1358577-77-1 5-(1,3-benzodioxol-5-yl)-1-[(2,4-dichlorophenyl)sulfonyl]-1H-tetrazole 

Relevant articles and documents

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Sulfonyl chloride as a disposable electron withdrawing substituent in halex fluorinations

Syntheses of 1,3-difluorobenzene and 2,6-difluorotoluene are described via chlorosulfonation, catalytic Halex-fluorination, and desulfination of 1,3-dichlorobenzene and 2,6-dichlorotoluene.