5-Chloro-3-phenyl-1-benzofuran-2-carboxylic acid

Base Information

Chemical Name:5-Chloro-3-phenyl-1-benzofuran-2-carboxylic acid
CAS No.:26965-47-9
Molecular Formula:C15H9 Cl O3
Molecular Weight:272.68
Hs Code.:2932999099
DSSTox Substance ID:DTXSID90597151
Nikkaji Number:J2.890.391J
Wikidata:Q82492647
Mol file:26965-47-9.mol

Synonyms:26965-47-9;5-chloro-3-phenylbenzofuran-2-carboxylic acid;5-CHLORO-3-PHENYL-1-BENZOFURAN-2-CARBOXYLIC ACID;2-Benzofurancarboxylicacid, 5-chloro-3-phenyl-;5-Chloro-3-phenyl-2-benzofurancarboxylic acid;5-chloro-3-phenyl-1-benzo[b]furan-2-carboxylic acid;SCHEMBL8401426;DTXSID90597151;URKXSHCRWIOSAN-UHFFFAOYSA-N;AKOS011665445

Suppliers and Price of 5-Chloro-3-phenyl-1-benzofuran-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-CHLORO-3-PHENYL-1-BENZOFURAN-2-CARBOXYLIC ACID 95.00%
5MG
$ 503.04

Total 3 raw suppliers

Chemical Property of 5-Chloro-3-phenyl-1-benzofuran-2-carboxylic acid

Chemical Property:

PSA：50.44000
LogP:4.45140
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:272.0240218
Heavy Atom Count:19
Complexity:340

Purity/Quality:

99% ^*data from raw suppliers

5-CHLORO-3-PHENYL-1-BENZOFURAN-2-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(OC3=C2C=C(C=C3)Cl)C(=O)O

Technology Process of 5-Chloro-3-phenyl-1-benzofuran-2-carboxylic acid

There total 3 articles about 5-Chloro-3-phenyl-1-benzofuran-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 27006-00-4
ethyl 5-chloro-3-phenyl-1-benzofuran-2-carboxylate

: 26965-47-9
5-chloro-3-phenylbenzofuran-2-carboxylic acid

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 20 ℃;
DOI:10.3987/COM-10-12070

Reference yield:

: 85-19-8
(5-chloro-2-hydroxyphenyl)phenylmethanone

: 26965-47-9
5-chloro-3-phenylbenzofuran-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / acetone / 0.5 h / Inert atmosphere

1.2: Inert atmosphere; Reflux

2.1: sodium hydroxide / tetrahydrofuran / 20 °C

With potassium carbonate; sodium hydroxide; In tetrahydrofuran; acetone;
DOI:10.3987/COM-10-12070