27006-00-4Relevant academic research and scientific papers
Convenient synthesis of some 3-phenyl-1-benzofuran-2-carboxylic acid derivatives as new potential inhibitors of ClC-Kb channels
Piemontese, Luca,Carbonara, Giuseppe,Fracchiolla, Giuseppe,Laghezza, Antonio,Tortorella, Paolo,Loiodice, Fulvio
experimental part, p. 2865 - 2872 (2011/04/24)
Improved experimental conditions were carried out for the preparation in high yields of some 3-phenyl-1-benzofuran-2-carboxylic acids, potent inhibitors of ClC-K chloride channels. A one-pot condensation-cyclization was set up starting from different 2-hy
One-pot synthesis of N-methylindoles from N-methylanilines and of benzofurans from phenols using transition-metal carbene X-H insertion reactions
Honey, Mark A.,Blake, Alexander J.,Campbell, Ian B.,Judkins, Brian D.,Moody, Christopher J.
experimental part, p. 8995 - 9001 (2010/03/01)
Transition-metal carbene X-H insertion reactions (X=N or O) have been employed in the simple conversion of anilines and phenols into indoles and benzofurans, respectively. Thus copper(II) catalyzed N-H insertion reactions of α-diazo-β-ketoesters with N-me
