N-TERTIARY BUTYL-N''-PHENYLCARBODIIMIDE

Base Information

• Chemical Name: N-TERTIARY BUTYL-N''-PHENYLCARBODIIMIDE
• CAS No.: 21848-95-3
• Molecular Formula: C11H14 N2
• Molecular Weight: 174.246
• Hs Code.: 29252900
• Mol file: 21848-95-3.mol

Synonyms:Carbodiimide,butylphenyl- (7CI,8CI); 1-Butyl-3-phenylcarbodiimide; Butylphenylcarbodiimide;N-Butyl-N'-phenylcarbodiimide

Chemical Property of N-TERTIARY BUTYL-N''-PHENYLCARBODIIMIDE

Chemical Property:

• PSA: 24.72000
• LogP: 3.29210

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-TERTIARY BUTYL-N''-PHENYLCARBODIIMIDE

There total 5 articles about N-TERTIARY BUTYL-N''-PHENYLCARBODIIMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3-n-butyl-1-phenylthiourea (6336-01-2) → 2-hydroxypyridin (142-08-5) + N-phenyl-N'-(n-butyl)carbodiimide (21848-95-3)

Guidance literature:

With di-2-pyridyl thionocarbonate; dmap; In acetonitrile; for 1h; Ambient temperature;

DOI:10.1016/S0040-4039(00)98578-2

Reference yield: 90.0%

N-butyl-N'-phenylurea (3083-88-3) → N-phenyl-N'-(n-butyl)carbodiimide (21848-95-3)

Guidance literature:

With triphenylphosphine dibromide 1:1 addition complex; triethylamine; In dichloromethane; at 0 ℃; for 60h;

DOI:10.1055/s-1981-29454

Reference yield:

n-butyl isonitrile (2769-64-4) + Phenyl azide (622-37-7) → N-phenyl-N'-(n-butyl)carbodiimide (21848-95-3)

Guidance literature:

Phenyl azide; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; for 0.0833333h; Sealed tube; Inert atmosphere; Green chemistry;

n-butyl isonitrile; In tetrahydrofuran; at 20 ℃; for 5h; Sealed tube; Inert atmosphere; Green chemistry;

DOI:10.1039/c5cc05981j

upstream raw materials:

N-butyl-N'-phenylurea

3-n-butyl-1-phenylthiourea

phenyl isothiocyanate

aniline

Downstream raw materials:

3-phenyl-1,3-oxazin-2-(N-n-butyl)imine

2-butylimino-5-ethyl-3-phenyl-1,3-oxazolidine

2-butylimino-4-ethyl-3-phenyl-1,3-oxazolidine

Butyl-[4-methoxymethyl-3-phenyl-oxazolidin-(2Z)-ylidene]-amine