tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate

Base Information

Chemical Name:tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate
CAS No.:142683-59-8
Molecular Formula:C₂₃H₃₉NO₆Si
Molecular Weight:453.651
Hs Code.:

Synonyms:tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate

Suppliers and Price of tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate

There total 5 articles about tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 142683-58-7
tert-butyl (S,Z)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxy-2-pentenoate

: 142683-59-8
tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate

Guidance literature:: With hydrogen; (R,R)-⁺BF4^-; In methanol; for 12h; under 2250.2 Torr; Ambient temperature;
DOI:10.1055/s-1992-26142

Reference yield:

: 118553-53-0
rac-tert-butyl 2-<(benzyloxy)carbonylamino>-2-(dimethoxyphosphoryl)-acetate

: 142683-59-8
tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate

Guidance literature:: Multi-step reaction with 4 steps

1: 1) DBU / 1) CH₂Cl₂, room temperature, 15 min, 2) a) -20 deg C, 15 min, b) to room temperature, 1 h

2: 80 percent / 1 N aq. HCl / dioxane; H₂O / 1 h / 80 °C

4: 99 percent / H₂ / (R,R)-BF₄ / methanol / 12 h / 2250.2 Torr / Ambient temperature

With hydrogenchloride; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; (R,R)-⁺BF4^-; In 1,4-dioxane; methanol; water;
DOI:10.1055/s-1992-26142

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 142683-59-8
tert-butyl (2S,4S)-2-benzyloxycarbonylamino-5-tert-butyldimethylsiloxy-4-hydroxypentanoate

Guidance literature:: Multi-step reaction with 2 steps

2: 99 percent / H₂ / (R,R)-BF₄ / methanol / 12 h / 2250.2 Torr / Ambient temperature

With hydrogen; (R,R)-⁺BF4^-; In methanol;
DOI:10.1055/s-1992-26142