formaldehyde bis(p-tert-butylphenyl) thioacetal

Base Information

• Chemical Name: formaldehyde bis(p-tert-butylphenyl) thioacetal
• CAS No.: 18068-20-7
• Molecular Formula: C₂₁H₂₈S₂
• Molecular Weight: 344.585
• Mol file: 18068-20-7.mol

Synonyms:formaldehyde bis(p-tert-butylphenyl) thioacetal

Chemical Property of formaldehyde bis(p-tert-butylphenyl) thioacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of formaldehyde bis(p-tert-butylphenyl) thioacetal

There total 3 articles about formaldehyde bis(p-tert-butylphenyl) thioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

carbon dioxide (124-38-9,18923-20-1) + 4-t-butylbenzenethiol (2396-68-1) → formaldehyde bis(p-tert-butylphenyl) thioacetal (18068-20-7)

Guidance literature:

carbon dioxide; 4-t-butylbenzenethiol; With sodium tetrahydroborate; In 1,4-dioxane; at 80 ℃; for 0.5h; under 760.051 Torr; Schlenk technique; Sealed tube;

With iodine; In 1,4-dioxane; at 100 ℃; for 24h; under 760.051 Torr; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.8b02730

Reference yield: 76.0%

nitromethane (75-52-5) + 4-t-butylbenzenethiol (2396-68-1) → formaldehyde bis(p-tert-butylphenyl) thioacetal (18068-20-7)

Guidance literature:

With lithium perchlorate; scandium tris(trifluoromethanesulfonate); at 25 ℃; for 8h; Molecular sieve; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01831

Reference yield: 47.0%

S-(fluoromethyl) benzenesulfonothioate + p-tert-butylphenylboronic acid (123324-71-0) → formaldehyde bis(p-tert-butylphenyl) thioacetal (18068-20-7)

Guidance literature:

With sodium hydrogencarbonate; copper(II) sulfate; In methanol; at 25 ℃; for 14h; Schlenk technique; Inert atmosphere;

DOI:10.1002/anie.201705633

upstream raw materials:

p-tert-butylphenylboronic acid

carbon dioxide

4-t-butylbenzenethiol

nitromethane

Downstream raw materials:

6,6-bis((p-tert-butylphenyl)thio)bicyclo<3.1.0>hexane

1,1-bis(phenylthio)-6,6-bis-((p-tertbutylphenyl)thio)hexane

1,1-bis(phenylthio)-4,4-bis((p-tert-butylphenyl)thio)butane

1,1,6,6-tetrakis((p-tert-butylphenyl)thio)hexane