N₁-benzyl-N₈-norcymserine

Base Information

• Chemical Name: N₁-benzyl-N₈-norcymserine
• CAS No.: 290294-30-3
• Molecular Formula: C₂₈H₃₁N₃O₂
• Molecular Weight: 441.573
• Mol file: 290294-30-3.mol

Synonyms:N₁-benzyl-N₈-norcymserine

Chemical Property of N₁-benzyl-N₈-norcymserine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₁-benzyl-N₈-norcymserine

There total 5 articles about N₁-benzyl-N₈-norcymserine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-isopropylphenylisocyanate (31027-31-3) + N1-benzyl-bis-noreseroline (290294-28-9) → N1-benzyl-N8-norcymserine (290294-30-3)

Guidance literature:

With sodium; In diethyl ether;

DOI:10.1016/S0040-4039(00)00740-1

Reference yield:

eseroline (469-22-7) → N1-benzyl-N8-norcymserine (290294-30-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 66 percent / KOH / dimethylsulfoxide

2: 19 percent / pyridinium dichromate; NaHCO₃ / CH₂Cl₂ / 2 h / ice-bath

3: 85 percent / sodium borohydride / tetrahydrofuran

4: 97 percent / Na / diethyl ether

With potassium hydroxide; sodium tetrahydroborate; dipyridinium dichromate; sodium; sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; dichloromethane; dimethyl sulfoxide; 1: Methylation / 1: Substitution / 2: Oxidation / 3: Reduction / 4: Condensation;

DOI:10.1016/S0040-4039(00)00740-1

Reference yield:

benzylamine (100-46-9) → N1-benzyl-N8-norcymserine (290294-30-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 66 percent / KOH / dimethylsulfoxide

2: 19 percent / pyridinium dichromate; NaHCO₃ / CH₂Cl₂ / 2 h / ice-bath

3: 85 percent / sodium borohydride / tetrahydrofuran

4: 97 percent / Na / diethyl ether

With potassium hydroxide; sodium tetrahydroborate; dipyridinium dichromate; sodium; sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; dichloromethane; dimethyl sulfoxide; 1: Methylation / 1: Substitution / 2: Oxidation / 3: Reduction / 4: Condensation;

DOI:10.1016/S0040-4039(00)00740-1

upstream raw materials:

4-isopropylphenylisocyanate

N¹-benzyl-bis-noreseroline

benzylamine

eseroline

Downstream raw materials:

(-)-N¹,N⁸-bisnorcymserine