(+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate

Base Information

• Chemical Name: (+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate
• CAS No.: 268551-16-2
• Molecular Formula: C₁₅H₁₅F₃N₂O₅S
• Molecular Weight: 392.356
• Mol file: 268551-16-2.mol

Synonyms:(+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate

Chemical Property of (+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate

There total 3 articles about (+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trifluoromethylsulfonic anhydride (358-23-6) + (+/-)-(1-hydroxy-3-phenylpropyl)(methoxymethoxy)methane-1,1-dicarbonitrile (268551-15-1) → (+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate (268551-16-2)

Guidance literature:

In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/S0040-4020(00)00040-5

Reference yield:

3-phenyl-propionaldehyde (104-53-0) → (+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate (268551-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / CH₂Cl₂ / 24 h / 20 °C

2: 127.2 mg / CH₂Cl₂ / 0.5 h / 0 °C

In dichloromethane; 1: Addition / 2: sulfonylation;

DOI:10.1016/S0040-4020(00)00040-5

Reference yield:

(methoxymethoxy)methane-1,1-dicarbonitrile → (+/-)-1-[dicyano(methoxymethoxy)methyl]-3-phenylpropyl(trifluoromethyl)-sulfonate (268551-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / CH₂Cl₂ / 24 h / 20 °C

2: 127.2 mg / CH₂Cl₂ / 0.5 h / 0 °C

In dichloromethane; 1: Addition / 2: sulfonylation;

DOI:10.1016/S0040-4020(00)00040-5

upstream raw materials:

trifluoromethylsulfonic anhydride

(+/-)-(1-hydroxy-3-phenylpropyl)(methoxymethoxy)methane-1,1-dicarbonitrile

3-phenyl-propionaldehyde

Downstream raw materials:

(+/-)-(1-azido-3-phenylpropyl)(methoxymethoxy)methane-1,1-dicarbonitrile