3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid

Base Information

• Chemical Name: 3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid
• CAS No.: 607356-44-5
• Molecular Formula: C₉H₈N₄O₆S₃
• Molecular Weight: 364.384
• Mol file: 607356-44-5.mol

Synonyms:3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid

Chemical Property of 3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid

There total 1 articles about 3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-amino-1, 3, 4-thiadiazole-2-sulfonamide (14949-00-9) + 3-Carboxybenzenesulfonyl chloride (4025-64-3) → 3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid (607356-44-5)

Guidance literature:

With sodium hydroxide; at 20 ℃;

DOI:10.1016/S0960-894X(03)00580-8

Reference yield:

4-(nitrooxy)butyl bromide (146563-40-8) + 3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid (607356-44-5) → C13H15N5O9S3 (1033598-26-3)

Guidance literature:

With potassium carbonate; sodium iodide; In dichloromethane; N,N-dimethyl acetamide; at 20 ℃;

DOI:10.1016/j.bmcl.2011.04.046

Reference yield:

1-O-Dimethylaminoethyl-ethylenglykol (1704-62-7) + 3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid (607356-44-5) → 3-(5-sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-benzoic acid 2-(2-dimethylamino-ethoxy)-ethyl ester

Guidance literature:

With TEA; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 4 ℃;

DOI:10.1016/S0960-894X(03)00580-8

upstream raw materials:

5-amino-1, 3, 4-thiadiazole-2-sulfonamide

3-Carboxybenzenesulfonyl chloride

Downstream raw materials:

C₂₃H₂₃N₅O₁₂S₃

C₁₃H₁₅N₅O₉S₃