3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine

Base Information

• Chemical Name: 3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine
• CAS No.: 1383851-08-8
• Molecular Formula: C₃₀H₃₃N
• Molecular Weight: 407.599
• Mol file: 1383851-08-8.mol

Synonyms:3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine

Chemical Property of 3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine

There total 9 articles about 3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

N-[2,2,2-trifluoro-1-phenylethylidene]aniline + 3,5-bis(2',6'-dimethylphenyl)-1-mesitylpyridin-1-ium trifluoromethanesulfonate (1383851-01-1) → 3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine (1383851-08-8) + phenyl[2-(2-phenyl-1,1,1-trifluoroethyl)] amine (191084-66-9)

Guidance literature:

With hydrogen; lithium hexamethyldisilazane; In toluene; at 50 ℃; for 5h; under 37503.8 Torr; Time; Inert atmosphere; Glovebox;

DOI:10.1002/anie.201503233

Reference yield: 33.0%

3,5-bis(2',6'-dimethylphenyl)-1-mesitylpyridin-1-ium trifluoromethanesulfonate (1383851-01-1) → 3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine (1383851-08-8) + 7,9-bis(2,6-dimethylphenyl)-2,4-dimethylpyrido[1,2-a]indole (1383851-10-2)

Guidance literature:

With hydrogen; lithium hexamethyldisilazane; In toluene; at 50 ℃; for 5h; under 37503.8 Torr; Pressure; Inert atmosphere; Glovebox; Autoclave;

DOI:10.1002/anie.201503233

Reference yield:

3,5-bis(2',6'-dimethylphenyl)-1-mesitylpyridin-1-ium trifluoromethanesulfonate (1383851-01-1) → 3,5-bis(2',6'-dimethylphenyl)-1-mesityl-1,2-dihydropyridine (1383851-08-8) + 3,5-bis(2,6-dimethylphenyl)-1-mesityl-1,4-dihydropyridine (1383851-09-9)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1039/c2cc33184e

upstream raw materials:

3,5-dibromopyridine

3,5-bis(2',6'-dimethylphenyl)-1-mesitylpyridin-1-ium trifluoromethanesulfonate

3,5-bis(2,6-dimethylphenyl)pyridine

C₂₇H₂₄N₃O₄⁽¹⁺⁾*Cl^(1-)