N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-(4-hydroxy-3-nitrophenyl)acetamide

Base Information

• Chemical Name: N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-(4-hydroxy-3-nitrophenyl)acetamide
• CAS No.: 1033605-95-6
• Molecular Formula: C₁₆H₂₁N₃O₉
• Molecular Weight: 399.357
• Mol file: 1033605-95-6.mol

Synonyms:N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-(4-hydroxy-3-nitrophenyl)acetamide

Chemical Property of N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-(4-hydroxy-3-nitrophenyl)acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-(4-hydroxy-3-nitrophenyl)acetamide

There total 1 articles about N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-(4-hydroxy-3-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-acetamido-2-deoxy-β-D-glucopyranosylamine (4229-38-3,102039-79-2,115350-20-4,133677-75-5,137493-97-1) + 4-hydroxy-3-nitrophenylacetic acid (10463-20-4) → N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-(4-hydroxy-3-nitrophenyl)acetamide (1033605-95-6)

Guidance literature:

With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1021/ja802008q

Reference yield: 65.0%

N-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-(4-hydroxy-3-nitrophenyl)acetamide (1033605-95-6) + 5-acetamido-9-(biphenyl-4-carboxamido)-3,5,9-trideoxy-D-glycero-α-D-galacto-non-2-ulopyranosonic acid sodium salt → N-{4-O-{6-O-[5-acetamido-9-(biphenyl-4-carboxamido)-3,5,9-trideoxy-D-glycero-α-D-galacto-non-2-ulopyranosyl-2-onic acid sodium salt]-β-D-galactopyranosyl}-2-acetamido-2-deoxy-β-D-glucopyranosyl} 2-(4-hydroxy-3-nitrophenyl)acetamide

Guidance literature:

With Nesseria meningitidis CMP-NeuAc synthetase; human ST₆GaI sialyltransferase; GaIE-GaIT; magnesium chloride; manganese(ll) chloride; In various solvent(s); at 20 ℃; for 24h; pH=7.5;

DOI:10.1021/ja802008q

upstream raw materials:

2-acetamido-2-deoxy-β-D-glucopyranosylamine

4-hydroxy-3-nitrophenylacetic acid