parazoanthine C

Base Information

• Chemical Name: parazoanthine C
• CAS No.: 1185452-02-1
• Molecular Formula: C₁₆H₁₉N₅O₃
• Molecular Weight: 329.359
• Mol file: 1185452-02-1.mol

Synonyms:parazoanthine C

Chemical Property of parazoanthine C

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of parazoanthine C

There total 6 articles about parazoanthine C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

C15H17N3O3 + 3,5-dimethyl-1-pyrazolylformaminidium nitrate (38184-47-3) → parazoanthine C (1185452-02-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2015.04.040

Reference yield:

4-Hydroxyacetophenone (99-93-4) → parazoanthine C (1185452-02-1)

Guidance literature:

Multi-step reaction with 6 steps

1.1: potassium carbonate / acetone / 0.25 h / Reflux

1.2: 3 h / Reflux

2.1: bromine; acetic acid / 50 °C

3.1: potassium carbonate; tetrabutylammomium bromide / N,N-dimethyl-formamide / 50 °C / Inert atmosphere

3.2: 2 h / 50 °C / Inert atmosphere

4.1: sodium tetrahydroborate / ethanol / 1 h / 20 °C

5.1: toluene-4-sulfonic acid / toluene / 1 h / 110 °C

6.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With sodium tetrahydroborate; tetrabutylammomium bromide; bromine; potassium carbonate; toluene-4-sulfonic acid; acetic acid; N-ethyl-N,N-diisopropylamine; In ethanol; N,N-dimethyl-formamide; acetone; toluene;

DOI:10.1016/j.tet.2015.04.040

Reference yield:

1-(4-methoxyphenyl)ethanone (100-06-1) → parazoanthine C (1185452-02-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: bromine; acetic acid / 50 °C

2.1: potassium carbonate; tetrabutylammomium bromide / N,N-dimethyl-formamide / 50 °C / Inert atmosphere

2.2: 2 h / 50 °C / Inert atmosphere

3.1: sodium tetrahydroborate / ethanol / 1 h / 20 °C

4.1: toluene-4-sulfonic acid / toluene / 1 h / 110 °C

5.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With sodium tetrahydroborate; tetrabutylammomium bromide; bromine; potassium carbonate; toluene-4-sulfonic acid; acetic acid; N-ethyl-N,N-diisopropylamine; In ethanol; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.tet.2015.04.040

upstream raw materials:

4-Hydroxyacetophenone

1-(4-methoxyphenyl)ethanone

2-Bromo-4'-methoxyacetophenone

3,5-dimethyl-1-pyrazolylformaminidium nitrate

Downstream raw materials:

parazoanthine B