4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride

Base Information

• Chemical Name: 4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride
• CAS No.: 1293973-89-3
• Molecular Formula: C₂₀H₁₁N₃O₃
• Molecular Weight: 341.326
• Mol file: 1293973-89-3.mol

Synonyms:4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride

Chemical Property of 4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride

There total 2 articles about 4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.6%

6-azido-1H,3H-benzo[de]isochromene-1,3-dione (1262149-88-1) + phenylacetylene (536-74-3) → 4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride (1293973-89-3)

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol;

DOI:10.1016/j.ejmech.2011.01.050

Reference yield:

4-bromo-1,8-naphthalenedicarboxylic anhydride (81-86-7) → 4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride (1293973-89-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide / water; N,N-dimethyl-formamide / 5 h / 20 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol

With sodium azide; copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; N,N-dimethyl-formamide; tert-butyl alcohol; 2: Huisgen cycloaddition;

DOI:10.1016/j.ejmech.2011.01.050

Reference yield: 87.0%

4-(4-phenyl-[1,2,3]-triazol-1-yl)-1,8-naphthalic anhydride (1293973-89-3) + N-butylamine (109-73-9,85404-21-3) → N-butyl-4-(4-phenyl-[1,2,3]-triazol-1-yl)-naphthalimide (1293973-95-1)

Guidance literature:

In ethanol; for 3h; Reflux;

DOI:10.1016/j.ejmech.2011.01.050

upstream raw materials:

6-azido-1H,3H-benzo[de]isochromene-1,3-dione

phenylacetylene

4-bromo-1,8-naphthalenedicarboxylic anhydride

Downstream raw materials:

N-(2-(piperazin-1-yl)ethyl)-4-(4-phenyl-[1,2,3]-triazol-1-yl)-naphthalimide

N-(2-hydroxy-ethyl)-4-(4-phenyl-[1,2,3]-triazol-1-yl)-naphthalimide

N-butyl-4-(4-phenyl-[1,2,3]-triazol-1-yl)-naphthalimide

N-(2-(dimethylamino)ethyl)-4-(4-phenyl-[1,2,3]-triazol-1-yl)-naphthalimide