25,27-Dipropoxycalix[4]arene

Base Information

• Chemical Name: 25,27-Dipropoxycalix[4]arene
• CAS No.: 143406-35-3
• Molecular Formula: C₃₄H₃₆O₄
• Molecular Weight: 508.657
• DSSTox Substance ID: DTXSID40369926
• Nikkaji Number: J645.056C
• Wikidata: Q82157214
• ChEMBL ID: CHEMBL2430576
• Mol file: 143406-35-3.mol

Synonyms:162301-48-6;25,27-DIPROPOXYCALIX[4]ARENE;25,27-Bis(1-propyloxy)calix[4]arene-26,28-diol;26,28-dipropoxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaene-25,27-diol;CHEMBL2430576;SCHEMBL12856732;DTXSID40369926;AKOS003615667;F1170-0232;2,6'-(2-Propoxy-1,3-phenylenebismethylene)-2',6-(2-propoxy-1,3-phenylenebismethylene)diphenol;26,28-dipropoxypentacyclo[19.3.1.1?,?.1?,??.1??,??]octacosa-1(25),3(28),4,6,9,11,13(27),15(26),16,18,21,23-dodecaene-25,27-diol;26,28-Dipropoxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,27-diol

Chemical Property of 25,27-Dipropoxycalix[4]arene

Chemical Property:

• XLogP3: 8.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 508.26135963
• Heavy Atom Count: 38
• Complexity: 596

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCOC1=C2CC3=C(C(=CC=C3)CC4=C(C(=CC=C4)CC5=CC=CC(=C5O)CC1=CC=C2)OCCC)O

Technology Process of 25,27-Dipropoxycalix[4]arene

There total 10 articles about 25,27-Dipropoxycalix[4]arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

25,26,27,28-tetrakis(hydroxy)calix[4]arene (248590-47-8,74568-07-3) + 1-iodo-propane (107-08-4) → 25,27-dihydroxy-26,28-dipropoxycalix[4]arene (143406-35-3,162301-48-6)

Guidance literature:

With potassium carbonate; In acetonitrile; for 18h; Heating;

Reference yield: 95.0%

25,26,27,28-tetrakis(hydroxy)calix[4]arene (248590-47-8,74568-07-3) + propyl bromide (106-94-5) → 25,27-dihydroxy-26,28-dipropoxycalix[4]arene (143406-35-3,162301-48-6)

Guidance literature:

With potassium carbonate; In acetonitrile; for 24h; Heating;

DOI:10.1021/jo800301m

Reference yield: 75.0%

25,27-dipropoxy-26,28-diacetoxycalix[4]arene (159644-99-2) → 25,27-dihydroxy-26,28-dipropoxycalix[4]arene (143406-35-3,162301-48-6)

Guidance literature:

25,27-dipropoxy-26,28-diacetoxycalix[4]arene; With sodium hydroxide; In tetrahydrofuran; ethanol; for 24h; Reflux;

With hydrogenchloride; In chloroform; water;

DOI:10.1016/j.tet.2011.03.010

upstream raw materials:

25,26,27,28-tetrakis(hydroxy)calix[4]arene

propyl bromide

1-iodo-propane

25,26-diacetoxy-27-propoxy-28-hydroxycalix[4]arene

Downstream raw materials:

25,26,27,28-tetrapropyloxycalix[4]arene

5,17-dibromo-26,28-dihydroxy-25,27-bis(1-propyloxy)calix<4>arene

25,27-bis(2-p-toluenesulfonyloxyethyloxy)-26,28-bis(1-propyloxy)calix[4]arene, 1,3-alternate

C₄₀H₄₆O₆