4-(4-Bromophenyl)azetidin-2-one

Base Information

Chemical Name:4-(4-Bromophenyl)azetidin-2-one
CAS No.:103247-89-8
Molecular Formula:C₉H₈BrNO
Molecular Weight:226.073
Hs Code.:
European Community (EC) Number:839-187-6
Nikkaji Number:J3.057.095B
Mol file:103247-89-8.mol

Synonyms:4-(4-bromophenyl)azetidin-2-one;4-(4-Bromophenyl)-2-azetidinone;103247-89-8;4-(p-bromophenyl)-2-azetidinone;AKOS013992432;EN300-299306;F79401;F8884-2283;Z1238837631

Suppliers and Price of 4-(4-Bromophenyl)azetidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Bromophenyl)azetidin-2-one
50mg
$ 90.00

Acrotein
4-(4-Bromophenyl)-2-azetidinone 97%
0.5g
$ 302.50

Total 5 raw suppliers

Chemical Property of 4-(4-Bromophenyl)azetidin-2-one

Chemical Property:

Melting Point:104-108 °C(Solv: isopropyl ether (108-20-3))
Boiling Point:399.4±42.0 °C(Predicted)
PKA:14.89±0.40(Predicted)
Density:1.571±0.06 g/cm3(Predicted)
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:224.97893
Heavy Atom Count:12
Complexity:187

Purity/Quality:

99% ^*data from raw suppliers

4-(4-Bromophenyl)azetidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC1=O)C2=CC=C(C=C2)Br

Technology Process of 4-(4-Bromophenyl)azetidin-2-one

There total 3 articles about 4-(4-Bromophenyl)azetidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 103247-88-7
4-(4-Bromphenyl)-2-azetidinon-N-sulfonylchlorid

: 103247-89-8
(+/-)-4-(4-bromophenyl)-2-azetidinone

Guidance literature:: With water; zinc; In methanol; at 60 ℃; for 0.5h;
DOI:10.1002/ardp.19863190305

Reference yield: 50.0%

: 1189-71-5
isocyanate de chlorosulfonyle

: 2039-82-9
1-bromo-4-ethenyl-benzene

: 103247-89-8
(+/-)-4-(4-bromophenyl)-2-azetidinone

Guidance literature:: isocyanate de chlorosulfonyle; 1-bromo-4-ethenyl-benzene; In toluene; at 20 ℃; for 8h;

With sodium carbonate; sodium sulfite; In water; toluene;
DOI:10.1002/adsc.200505434

Reference yield:

: 2039-82-9
1-bromo-4-ethenyl-benzene

: 103247-89-8
(+/-)-4-(4-bromophenyl)-2-azetidinone

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / diethyl ether / 1.) 40 deg C, 30 min, 2.) room temp., 8 h

2: 83 percent / Zn, H₂O / methanol / 0.5 h / 60 °C

With water; zinc; In methanol; diethyl ether;
DOI:10.1002/ardp.19863190305