2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione)

Base Information

• Chemical Name: 2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione)
• CAS No.: 1314403-21-8
• Molecular Formula: C₂₇H₂₃N₃O₅
• Molecular Weight: 469.497
• Mol file: 1314403-21-8.mol

Synonyms:2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione)

Chemical Property of 2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione)

There total 2 articles about 2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

bis(phthalimidylethyl)amine (63563-83-7) + salicylaldehyde (90-02-8) → 2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione) (1314403-21-8)

Guidance literature:

bis(phthalimidylethyl)amine; salicylaldehyde; In 1,2-dichloro-ethane;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 24h;

DOI:10.1021/ic102185y

Reference yield:

phthalic anhydride (85-44-9) → 2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione) (1314403-21-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetic acid / 2 h / 135 °C

2.1: 1,2-dichloro-ethane / 0.17 h

2.2: 24 h / 20 °C

With acetic acid; In 1,2-dichloro-ethane;

DOI:10.1021/acs.inorgchem.0c01831

Reference yield: 85.0%

2,2′-(((2-hydroxybenzyl)azanediyl)bis(ethane-2,1-diyl))bis-(isoindoline-1,3-dione) (1314403-21-8) → N,N-bis(2-aminoethyl)-N-(2-hydroxybenzyl)amine

Guidance literature:

With hydrazine hydrate; In ethanol; chloroform; at 20 ℃; for 24h;

DOI:10.1021/ic102185y

upstream raw materials:

bis(phthalimidylethyl)amine

salicylaldehyde

phthalic anhydride