7β-Acetoxy-3-oxo-5β-cholan-24-oic acid methyl ester

Base Information

Chemical Name:7β-Acetoxy-3-oxo-5β-cholan-24-oic acid methyl ester
CAS No.:60354-41-8
Molecular Formula:C₂₇H₄₂O₅
Molecular Weight:446.627
Hs Code.:
Mol file:60354-41-8.mol

Synonyms:methyl 7α-acetoxy-3-oxo-5β-cholan-24-oate

Suppliers and Price of 7β-Acetoxy-3-oxo-5β-cholan-24-oic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 7β-Acetoxy-3-oxo-5β-cholan-24-oic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 7β-Acetoxy-3-oxo-5β-cholan-24-oic acid methyl ester

There total 1 articles about 7β-Acetoxy-3-oxo-5β-cholan-24-oic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14773-00-3
methyl (5β,7α)-12-hydroxy-3-oxo-cholan-24-oate

: 108-24-7
acetic anhydride

: 60354-41-8
methyl 7α-acetoxy-3-oxo-5β-cholan-24-oate

Guidance literature:: With dmap; triethylamine; In dichloromethane; for 1.5h;
DOI:10.1248/cpb.34.2890

Reference yield: 64.0%

: 60354-41-8
methyl 7α-acetoxy-3-oxo-5β-cholan-24-oate

: 1576-35-8
toluene-4-sulfonic acid hydrazide

: 96475-66-0
C₃₄H₅₀N₂O₆S

Guidance literature:: In acetic acid; for 12h; Ambient temperature;
DOI:10.1055/s-1984-31036

Reference yield:

: 60354-41-8
methyl 7α-acetoxy-3-oxo-5β-cholan-24-oate

: 99598-04-6,107368-95-6,108179-87-9
1β.3α,7α-trihydroxy-5β-cholan-24-oic acid

Guidance literature:: Multi-step reaction with 8 steps

1: Br₂ / acetic acid / 1 h / Ambient temperature

2: 2.13 g / Li₂CO₃, LiBr / dimethylformamide / 4 h / 80 °C

3: 987 mg / Zn dust / acetone; acetic acid / 1 h / Ambient temperature

4: 30 percent H₂O₂, 2 N NaOH / tetrahydrofuran; ethanol / 6 h / Ambient temperature

5: diethyl ether

6: 336 mg / Cr(OAc)2 / ethanol / 2 h / Ambient temperature

7: 241 mg / NaBH₄ / propan-2-ol / 0.5 h

8: 154 mg / 2 N LiOH / methanol / 1 h / Heating

With lithium hydroxide; sodium hydroxide; sodium tetrahydroborate; dihydrogen peroxide; bromine; lithium carbonate; chromium(II) acetate; lithium bromide; zinc; In tetrahydrofuran; methanol; diethyl ether; ethanol; acetic acid; N,N-dimethyl-formamide; isopropyl alcohol; acetone;
DOI:10.1248/cpb.34.2890