Technology Process of C22H24O4
There total 5 articles about C22H24O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C31H32BrNO4;
With
tert.-butyl lithium;
In
tetrahydrofuran;
at -70 - -20 ℃;
Inert atmosphere;
With
phosphoric acid;
DOI:10.1021/op5000489
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine / tetrahydrofuran / Inert atmosphere
2: sodium iodide / Inert atmosphere
3: lithium hexamethyldisilazane; 1,4-diaza-bicyclo[2.2.2]octane / methanol; tetrahydrofuran / 10 - 30 °C / Inert atmosphere; Large scale
4: lithium hexamethyldisilazane / -70 - -20 °C / Inert atmosphere
5: tert.-butyl lithium / tetrahydrofuran / -70 - -20 °C / Inert atmosphere
With
1,4-diaza-bicyclo[2.2.2]octane; tert.-butyl lithium; triethylamine; sodium iodide; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol;
DOI:10.1021/op5000489
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium iodide / Inert atmosphere
2: lithium hexamethyldisilazane; 1,4-diaza-bicyclo[2.2.2]octane / methanol; tetrahydrofuran / 10 - 30 °C / Inert atmosphere; Large scale
3: lithium hexamethyldisilazane / -70 - -20 °C / Inert atmosphere
4: tert.-butyl lithium / tetrahydrofuran / -70 - -20 °C / Inert atmosphere
With
1,4-diaza-bicyclo[2.2.2]octane; tert.-butyl lithium; sodium iodide; lithium hexamethyldisilazane;
In
tetrahydrofuran; methanol;
DOI:10.1021/op5000489
