1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one

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Chemical Name:1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one
CAS No.:1038920-27-2
Molecular Formula:C₄₇H₄₁N₇O
Molecular Weight:719.889
Hs Code.:

Synonyms:1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one

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Chemical Property of 1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one

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Technology Process of 1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one

There total 2 articles about 1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 108-22-5
Isopropenyl acetate

: 1038920-35-2
5-chloro-2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridine

: 1038920-27-2
1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one

Guidance literature:: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; tributyltin methoxide; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 100 ℃; Product distribution / selectivity;

Reference yield: 77.4%

: 108-22-5
Isopropenyl acetate

: 1038919-65-1
(S)-5-bromo-2-ethyl-7-methyl-3-{5-[2-(1-trityl-1H-tetrazol-5-yl)-phenyl]-indan-1-yl}-3H-imidazo[4,5-b]pyridine

: 1038920-27-2
1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one

Guidance literature:: With tributyltin methoxide; bis(dibenzylideneacetone)-palladium⁽⁰⁾; 2′-(diphenylphosphino)-N,N′-dimethyl-(1,1′-biphenyl)-2-amine; In toluene; at 90 ℃; for 6h; Product distribution / selectivity;

Reference yield:

: 1038920-27-2
1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one

: 75-16-1
methylmagnesium bromide

: 1038920-33-0
1-((S)-2-ethyl-7-methyl-3-{5-[2-(1-trityl-1H-tetrazol-5-yl)-phenyl]-indan-1-yl}-3H-imidazo[4,5-b]pyridin-5-yl)-2-methyl-propan-2-ol

Guidance literature:: 1-(2-ethyl-7-methyl-3-((1S)-5-(2-(1-trityl-1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-3H-imidazo[4,5-b]pyridin-5-yl)propan-2-one; methylmagnesium bromide; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

With water; ammonium chloride; In tetrahydrofuran;