1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol

Base Information

• Chemical Name: 1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol
• CAS No.: 718621-10-4
• Molecular Formula: C₁₄H₁₄O₅S₂
• Molecular Weight: 326.394
• Mol file: 718621-10-4.mol

Synonyms:1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol

Chemical Property of 1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol

There total 1 articles about 1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

(2R,4R)-5-Benzyloxy-pentane-1,2,3,4-tetraol + 1,1'-Thiocarbonyldiimidazole (6160-65-2) → 1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-arabinitol (718621-08-0) + 1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol (718621-10-4)

Guidance literature:

In 1,4-dioxane; at 20 ℃;

DOI:10.1016/j.tet.2005.05.008

Reference yield: 65.0%

acetic anhydride (108-24-7) + 1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol (718621-10-4) → 2,3-di-O-acetyl-5-O-benzyl-1,4-thioanhydro-L-ribitol

Guidance literature:

1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol; With sodium sulfide; In dimethyl sulfoxide; at 80 ℃; for 1h;

acetic anhydride; In pyridine; Further stages.;

DOI:10.1016/j.tetlet.2004.03.197

Reference yield:

1-O-benzyl-2,3:4,5-di-O-thiocarbonyl-D-lyxitol (718621-10-4) → 1,4-anhydro-5-O-benzyl-L-xylitol (191792-33-3) + (2R,3S,4R)-2-Benzyloxymethyl-tetrahydro-furan-3,4-diol

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 16h; Title compound not separated from byproducts;

DOI:10.1016/j.tet.2005.05.008

upstream raw materials:

1,1'-Thiocarbonyldiimidazole

Downstream raw materials:

1,4-anhydro-5-O-benzyl-L-xylitol

Refernces