N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

Base Information

Chemical Name:N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide
CAS No.:1621190-62-2
Molecular Formula:C₂₇H₂₉F₄N₇O₄S₂
Molecular Weight:655.697
Hs Code.:

N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

Synonyms:N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

Suppliers and Price of N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

There total 5 articles about N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1313009-34-5
1-[4-[4[-5-(2-acetylphenyl)-4,5-dihydroisoxazol-3-yl]thiazol-2-yl]-1-piperidyl]-2-[3,5-bis(difluoromethyl)pyrazol-1-yl]ethanone

: methanesulfonyl hydrazone hydrochloride

: 1621190-62-2
N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

: C₂₇H₂₉F₄N₇O₄S₂

Guidance literature:: In ethanol; at 80 ℃; for 72h;

Reference yield:

: 1229003-42-2
2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-carbaldehyde

: 1621190-62-2
N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

: C₂₇H₂₉F₄N₇O₄S₂

Guidance literature:: Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol / 2.5 h / 20 °C

2: trifluoroacetic acid; [bis(acetoxy)iodo]benzene / methanol / 1.5 h / 20 °C

3: ethanol / 72 h / 80 °C

With [bis(acetoxy)iodo]benzene; hydroxylamine hydrochloride; sodium acetate; trifluoroacetic acid; In methanol; ethanol;

Reference yield:

: (4E)-2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-carbaldehyde oxime

: 1621190-62-2
N-[(Z)-1-[2-[3-[2-[1-[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]thiazol-4-yl]-4,5-dihydroisoxazol-5-yl]phenyl]ethylideneamino]methanesulfonamide

: C₂₇H₂₉F₄N₇O₄S₂

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid; [bis(acetoxy)iodo]benzene / methanol / 1.5 h / 20 °C

2: ethanol / 72 h / 80 °C

With [bis(acetoxy)iodo]benzene; trifluoroacetic acid; In methanol; ethanol;