N'-[(E)-(4-chlorophenyl)methylidene]pyridine-3-carbohydrazide

Base Information

Chemical Name:N'-[(E)-(4-chlorophenyl)methylidene]pyridine-3-carbohydrazide
CAS No.:89813-99-0
Molecular Formula:C₁₃H₁₀ClN₃O
Molecular Weight:259.695
Hs Code.:
European Community (EC) Number:684-950-7
NSC Number:748692
ChEMBL ID:CHEMBL2235148

Synonyms:CHEMBL2235148;N'-[(E)-(4-chlorophenyl)methylidene]pyridine-3-carbohydrazide;Niazid 4ClPhCHO;BDBM50237979;NSC748692;STK160745;AKOS001629627;NSC-748692;4-Chlorobenzaldehyde nicotinoyl hydrazone;SR-01000108624;SR-01000108624-1;NICOTINIC ACID (4-CHLORO-BENZYLIDENE)-HYDRAZIDE;N'-[(4-chlorophenyl)methylidene]pyridine-3-carbohydrazide;N-[(E)-(4-chlorophenyl)methyleneamino]pyridine-3-carboxamide

Suppliers and Price of N'-[(E)-(4-chlorophenyl)methylidene]pyridine-3-carbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N'-[(E)-(4-chlorophenyl)methylidene]pyridine-3-carbohydrazide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:259.0512396
Heavy Atom Count:18
Complexity:301

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CN=C1)C(=O)NN=CC2=CC=C(C=C2)Cl
Isomeric SMILES:C1=CC(=CN=C1)C(=O)N/N=C/C2=CC=C(C=C2)Cl

Technology Process of N'-[(E)-(4-chlorophenyl)methylidene]pyridine-3-carbohydrazide

There total 5 articles about N'-[(E)-(4-chlorophenyl)methylidene]pyridine-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 553-53-7
Nicotinic acid hydrazide

: 104-88-1
4-chlorobenzaldehyde

: 89813-99-0
(E)-N’-(4'-chlorobenzylidene)nicotinohydrazide

Guidance literature:: With acetic acid; In ethanol; Reflux;
DOI:10.1016/j.bmc.2017.02.044

Reference yield: 84.9%

: 553-53-7
Nicotinic acid hydrazide

: 104-88-1
4-chlorobenzaldehyde

: 89813-99-0
N₁-(4-chlorobenzylidene) nicotinohydrazide

Guidance literature:: In ethanol; Reflux;
DOI:10.1007/s00044-011-9664-7

Reference yield:

: 59-67-6
nicotinic acid

: 89813-99-0
N₁-(4-chlorobenzylidene) nicotinohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / Reflux

2: hydrazine hydrate / ethanol / 8 h / Reflux

3: ethanol / Reflux

With sulfuric acid; hydrazine hydrate; In ethanol;
DOI:10.1007/s00044-011-9664-7