Ethyl alpha-cyano-4-nitro-trans-cinnamate

Base Information

• Chemical Name: Ethyl alpha-cyano-4-nitro-trans-cinnamate
• CAS No.: 2017-89-2
• Molecular Formula: C12H10 N2 O4
• Molecular Weight: 246.222
• Hs Code.: 2916140090
• Mol file: 2017-89-2.mol

Synonyms:2-Propenoicacid, 2-cyano-3-(4-nitrophenyl)-, ethyl ester, (E)-; Cinnamic acid, a-cyano-p-nitro-, ethyl ester,(E)- (8CI)

Chemical Property of Ethyl alpha-cyano-4-nitro-trans-cinnamate

Chemical Property:

• PSA: 95.91000
• LogP: 2.58808

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl2-Cyano-3-(4-nitrophenyl)acrylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl alpha-cyano-4-nitro-trans-cinnamate

There total 22 articles about Ethyl alpha-cyano-4-nitro-trans-cinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-nitrobenzaldehdye (555-16-8) + ethyl 2-cyanoacetate (105-56-6) → (E)-ethyl 2-cyano-3-(4-nitrophenyl)acrylate (2017-89-2)

Guidance literature:

With L-proline; for 0.1h; microwave irradiation;

Reference yield: 100.0%

4-nitrobenzaldehdye (555-16-8) + ethyl 2-cyanoacetate (105-56-6) + (4-nitrophenyl)ethanone (100-19-6) → 2-cyano-3-(4-nitrophenyl)-2-propenoic acid ethyl ester (2017-89-2,2286-33-1,96238-12-9)

Guidance literature:

With SBA-15-supported poly(4-methylvinylpyridinium hydroxide) composite; In water; Reflux;

DOI:10.5012/bkcs.2010.31.9.2618

Reference yield: 99.6%

4-nitrobenzaldehdye (555-16-8) + ethyl 2-cyanoacetate (105-56-6) → 2-cyano-3-(4-nitrophenyl)-2-propenoic acid ethyl ester (2017-89-2,2286-33-1,96238-12-9)

Guidance literature:

aluminum oxide; In ethanol; for 0.5h; Heating;

DOI:10.1081/SCC-120016322

upstream raw materials:

ethanol

2-cyano-3-(4'-nitro-1'-phenyl)acrylic acid

4-nitrobenzaldehdye

ethyl 2-cyanoacetate

Downstream raw materials:

1-Cyano-2,2,3,3-tetramethoxy-4-(4-nitro-phenyl)-cyclobutanecarboxylic acid ethyl ester

5-amino-2-(4-nitro-benzylidene)-7-(4-nitro-phenyl)-3-oxo-2,3-dihydro-7H-thiazolo[3,2-a]pyridine-6,8-dicarboxylic acid diethyl ester

4-(4-Nitro-phenyl)-1-phenyl-1H-pyrazole-3,5-dicarboxylic acid diethyl ester

4-(4-nitrophenyl)-6-oxo-2-phenyl-1,6-dihydropyrimidine-5-carbonitrile