3-bromo-5-trimethylsilylbenzoic acid

Base Information

Chemical Name:3-bromo-5-trimethylsilylbenzoic acid
CAS No.:476195-73-0
Molecular Formula:C₁₀H₁₃BrO₂Si
Molecular Weight:273.202
Hs Code.:

Synonyms:3-bromo-5-trimethylsilylbenzoic acid

Suppliers and Price of 3-bromo-5-trimethylsilylbenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-bromo-5-trimethylsilylbenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-bromo-5-trimethylsilylbenzoic acid

There total 2 articles about 3-bromo-5-trimethylsilylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: 17878-23-8
3,5-dibromo-1-trimethylsilylbenzene

: 476195-73-0
3-bromo-5-trimethylsilylbenzoic acid

Guidance literature:: 3,5-dibromo-1-trimethylsilylbenzene; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 2.5h;

carbon dioxide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1.66667h; Further stages.;
DOI:10.1021/jo025723a

Reference yield:

: 626-39-1
1,3,5-trisbromobenzene

: 476195-73-0
3-bromo-5-trimethylsilylbenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / diethyl ether; hexane / 3 h / -78 °C

1.2: diethyl ether; hexane / -78 - 20 °C

2.1: n-BuLi / diethyl ether; hexane / 2.5 h / -78 °C

2.2: 5.82 g / tetrahydrofuran; hexane / 1.67 h / -78 - 20 °C

With n-butyllithium; In diethyl ether; hexane;
DOI:10.1021/jo025723a