1-(2-methoxyphenyl)-3-methyl-1H-pyrazol-5-amine

Base Information

Chemical Name:1-(2-methoxyphenyl)-3-methyl-1H-pyrazol-5-amine
CAS No.:91331-85-0
Molecular Formula:C₁₁H₁₃N₃O
Molecular Weight:203.244
Hs Code.:
DSSTox Substance ID:DTXSID601326295
ChEMBL ID:CHEMBL1529071
Mol file:91331-85-0.mol

Synonyms:1-(2-methoxyphenyl)-3-methyl-1H-pyrazol-5-amine;91331-85-0;2-(2-methoxyphenyl)-5-methylpyrazol-3-amine;2-(2-methoxyphenyl)-5-methyl-2H-pyrazol-3-ylamine;MLS000728952;SCHEMBL1826994;CHEMBL1529071;DTXSID601326295;HMS2733L09;STK682936;AKOS002665255;KS-6843;SMR000307230;CS-0330359;FT-0719839;2-(2-Methoxy-phenyl)-5-methyl-2H-pyrazol-3-ylamine

Suppliers and Price of 1-(2-methoxyphenyl)-3-methyl-1H-pyrazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Methoxyphenyl)-3-methyl-1H-pyrazol-5-amine 97%
1g
$ 457.00

Total 4 raw suppliers

Chemical Property of 1-(2-methoxyphenyl)-3-methyl-1H-pyrazol-5-amine

Chemical Property:

Melting Point:105-106 °C
Boiling Point:379.4±32.0 °C(Predicted)
PKA:3.74±0.10(Predicted)
Density:1.19±0.1 g/cm3(Predicted)
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:203.105862047
Heavy Atom Count:15
Complexity:212

Purity/Quality:

99% ^*data from raw suppliers

1-(2-Methoxyphenyl)-3-methyl-1H-pyrazol-5-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C(=C1)N)C2=CC=CC=C2OC

Technology Process of 1-(2-methoxyphenyl)-3-methyl-1H-pyrazol-5-amine

There total 4 articles about 1-(2-methoxyphenyl)-3-methyl-1H-pyrazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1118-61-2
3-Aminocrotononitrile

: 6971-45-5,57396-67-5
2-methoxyphenylhydrazine hydrochloride

: 91331-85-0
2-(2-methoxyphenyl)-5-methyl-2H-pyrazol-3-ylamine

Guidance literature:: 3-Aminocrotononitrile; 2-methoxyphenylhydrazine hydrochloride; With hydrogenchloride; In water; at 100 ℃; for 18h;

With sodium hydroxide; In water; pH=> 12;

Reference yield: 93.0%

: 1118-61-2
3-Aminocrotononitrile

: 18312-46-4
(2-methoxyphenyl)hydrazine

: 91331-85-0
2-(2-methoxyphenyl)-5-methyl-2H-pyrazol-3-ylamine

Guidance literature:: 3-Aminocrotononitrile; (2-methoxyphenyl)hydrazine; With hydrogenchloride; In water; for 12h; Reflux;

With sodium hydroxide; In water;
DOI:10.1016/j.bmc.2012.04.021

Reference yield: 20.0%

: 1118-61-2
3-Aminocrotononitrile

: 90-04-0
2-methoxy-phenylamine

: 91331-85-0
2-(2-methoxyphenyl)-5-methyl-2H-pyrazol-3-ylamine

Guidance literature:: 2-methoxy-phenylamine; With hydrogenchloride; sodium nitrite; In water; at -2 - 0 ℃; for 1h; Green chemistry;

With ascorbic acid; In water; at -2 - 0 ℃; Green chemistry;

3-Aminocrotononitrile; In water; at 45 - 90 ℃; Green chemistry;
DOI:10.1039/c3ra47541g