5-chloro-2-(2-chloro-6-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine

Base Information

• Chemical Name: 5-chloro-2-(2-chloro-6-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine
• CAS No.: 1612288-00-2
• Molecular Formula: C₁₉H₁₁Cl₂FN₂O₂S
• Molecular Weight: 421.279

Synonyms:5-chloro-2-(2-chloro-6-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine

Chemical Property of 5-chloro-2-(2-chloro-6-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine

Chemical Property:

Purity/Quality:

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Technology Process of 5-chloro-2-(2-chloro-6-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine

There total 1 articles about 5-chloro-2-(2-chloro-6-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

→ 5-chloro-2-(2-chloro-6-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine (1612288-00-2)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

In N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield: 35.0%

[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]boronic acid (344591-91-9) + 5-chloro-2-(2-chloro-6-fluorophenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine (1612288-00-2) → C18H11ClF4N4 (1612288-94-4)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; caesium carbonate; In 1,4-dioxane; at 110 ℃; for 4h; Inert atmosphere;

Downstream raw materials:

C₁₈H₁₁ClF₄N₄

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