N-Bsmoc-L-methionine

Base Information

Chemical Name:N-Bsmoc-L-methionine
CAS No.:197245-29-7
Molecular Formula:C15H17 N O6 S2
Molecular Weight:371.43
Hs Code.:
DSSTox Substance ID:DTXSID90428830
Nikkaji Number:J1.135.236G
Wikidata:Q82241662
Mol file:197245-29-7.mol

Synonyms:N-Bsmoc-L-methionine;197245-29-7;(2S)-2-[(1,1-dioxo-1-benzothiophen-2-yl)methoxycarbonylamino]-4-methylsulfanylbutanoic acid;(((1,1-Dioxidobenzo[b]thiophen-2-yl)methoxy)carbonyl)-L-methionine;L-Methionine, N-[[(1,1-dioxidobenzo[b]thien-2-yl)methoxy]carbonyl]-;Bsmoc-Met-OH;DTXSID90428830;AKOS024348912;N-[(1-Benzothiophene 1,1-dioxide)-2-ylmethoxycarbonyl]-L-methionine

Suppliers and Price of N-Bsmoc-L-methionine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-BSMOC-L-METHIONINE 95.00%
1G
$ 676.00

American Custom Chemicals Corporation
N-BSMOC-L-METHIONINE 95.00%
5MG
$ 502.80

Total 6 raw suppliers

Chemical Property of N-Bsmoc-L-methionine

Chemical Property:

Vapor Pressure:6.78E-19mmHg at 25°C
Melting Point:116°C
Refractive Index:1.615
Boiling Point:670.5°Cat760mmHg
Flash Point:359.3°C
PSA：146.94000
Density:1.44g/cm³
LogP:3.03250
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:371.04972961
Heavy Atom Count:24
Complexity:610

Purity/Quality:

99% ^*data from raw suppliers

N-BSMOC-L-METHIONINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSCCC(C(=O)O)NC(=O)OCC1=CC2=CC=CC=C2S1(=O)=O
Isomeric SMILES:CSCC[C@@H](C(=O)O)NC(=O)OCC1=CC2=CC=CC=C2S1(=O)=O

Technology Process of N-Bsmoc-L-methionine

There total 6 articles about N-Bsmoc-L-methionine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 63-68-3,26062-47-5,58576-49-1
L-methionine

: 197244-91-0
N-(benzothiophenesulfone-2-methyl)-N-succinimidyl carbonate

: 197245-29-7
Bsmoc-Met-OH

Guidance literature:: With triethylamine; In water; acetonitrile; for 0.75h; Ambient temperature; pH 8.5-9;
DOI:10.1021/jo982140l

Reference yield:

: 50779-55-0
benzothiophen-2-yllithium

: 197245-29-7
Bsmoc-Met-OH

Guidance literature:: Multi-step reaction with 5 steps

1: 2.) NaBH₄ / 2.) MeOH

2: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C

3: 36.1 g / tetrahydrofuran / -30 - 20 °C

4: 74 percent / CH₂Cl₂ / 20 h

5: 58 percent / Et₃N / acetonitrile; H₂O / 0.75 h / Ambient temperature; pH 8.5-9

With sodium perborate; sodium tetrahydroborate; triethylamine; In tetrahydrofuran; dichloromethane; water; acetic acid; acetonitrile;
DOI:10.1021/jo982140l

Reference yield:

: 17890-56-1
benzothiophene-2-methanol

: 197245-29-7
Bsmoc-Met-OH

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C

2: 36.1 g / tetrahydrofuran / -30 - 20 °C

3: 74 percent / CH₂Cl₂ / 20 h

4: 58 percent / Et₃N / acetonitrile; H₂O / 0.75 h / Ambient temperature; pH 8.5-9

With sodium perborate; triethylamine; In tetrahydrofuran; dichloromethane; water; acetic acid; acetonitrile;
DOI:10.1021/jo982140l