5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide

Base Information

Chemical Name:5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide
CAS No.:864961-46-6
Molecular Formula:C₁₃H₁₃BrFNO₃S₂
Molecular Weight:394.286
Hs Code.:

Synonyms:5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide

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Chemical Property of 5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide

Chemical Property:

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Technology Process of 5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide

There total 2 articles about 5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 864961-45-5
5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-oxoethyl]-methyl-amide

: 864961-46-6
5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide

Guidance literature:: With sodium tetrahydroborate; at 0 ℃;

Reference yield:

: 81597-52-6
5-bromo-N-methylthiophene-2-sulfonamide

: 864961-46-6
5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran / 20 °C

2: sodium tetrahydroborate / 0 °C

With sodium tetrahydroborate; sodium hydride; In tetrahydrofuran;