5-BroMo-thiophene-2-sulfonic acid M ethylaMide

Base Information

• Chemical Name: 5-BroMo-thiophene-2-sulfonic acid M ethylaMide
• CAS No.: 81597-52-6
• Molecular Formula: C5H6BrNO2S2
• Molecular Weight: 256.14100
• Hs Code.: 2935009090
• Mol file: 81597-52-6.mol

Synonyms:5-bromo-N-methylpicolinamide;5-bromo-N-methylthiophene-2-sulfonamide;5-bromo-N-methyl-2-pyridinecarboxamide;N-Methyl 5-bromopicolinamide;5-bromothiophene-2-sulfonic acid methyl-amide;

Chemical Property of 5-BroMo-thiophene-2-sulfonic acid M ethylaMide

Chemical Property:

• PSA: 82.79000
• LogP: 2.89040

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-thiophene-2-sulfonicacidmethylamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-BroMo-thiophene-2-sulfonic acid M ethylaMide

There total 4 articles about 5-BroMo-thiophene-2-sulfonic acid M ethylaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

→ 5-bromo-N-methylthiophene-2-sulfonamide (81597-52-6)

Guidance literature:

Reference yield: 19.0%

N-methyl-2-thiophenylsulfonamide (53442-30-1) → 5-bromo-N-methylthiophene-2-sulfonamide (81597-52-6)

Guidance literature:

With bromine; In chloroform; for 7h; Reflux;

Reference yield:

5-bromo-2-thiophenesulfonyl chloride (55854-46-1) + methylamine (74-89-5) → 5-bromo-N-methylthiophene-2-sulfonamide (81597-52-6)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; at 0 ℃; for 0.25h;

upstream raw materials:

5-bromo-2-thiophenesulfonyl chloride

methylamine

N-methyl-2-thiophenylsulfonamide

methylamine hydrochloride

Downstream raw materials:

5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-oxoethyl]-methyl-amide

5-bromothiophene-2-sulfonic acid [2-fluoro-2-(4-fluorophenyl)ethyl]-methyl-amide

5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide

5-Bromothiophene-2-sulfonic acid[2-(4-fluorophenyl)-2-methoxyethyl]-methyl-amide