2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine

Base Information

Chemical Name:2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine
CAS No.:1262414-32-3
Molecular Formula:C₂₅H₂₉N₃O₄
Molecular Weight:435.523
Hs Code.:

Synonyms:2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine

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Chemical Property of 2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine

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Technology Process of 2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine

There total 13 articles about 2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67843-74-7,24969-06-0,13403-37-7
(S)-epichlorohydrin

: 1262414-29-8
4-[3-(2-cyclopentyl-6-methoxypyridin-4-yl)-[1,2,4]oxadiazol-5-yl]-2-ethyl-6-methylphenol

: 1262414-32-3
2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine

Guidance literature:: With sodium hydroxide; In water; isopropyl alcohol; at 20 ℃; for 72h;

Reference yield:

: 51594-55-9,24969-06-0,13403-37-7
(R)-(-)-epichlorohydrin

: 1262414-29-8
4-[3-(2-cyclopentyl-6-methoxypyridin-4-yl)-[1,2,4]oxadiazol-5-yl]-2-ethyl-6-methylphenol

: 1262414-32-3
2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine

Guidance literature:: With water; sodium hydroxide; In isopropyl alcohol; at 20 ℃; for 72h;

Reference yield:

: 944327-07-5
4-benzyloxy-3-ethyl-5-methylbenzaldehyde

: 1262414-32-3
2-cyclopentyl-4-[5-((S)-3-ethyl-5-methyl-4-oxiranylmethoxy-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-pyridine

Guidance literature:: Multi-step reaction with 5 steps

1: 2-methyl-but-2-ene; sodium chlorite; sodium dihydrogenphosphate dihydrate / water; tert-butyl alcohol / 30 °C

2: N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / N,N-dimethyl-formamide / 1 h / 20 °C

3: 1,4-dioxane / 48 h / 115 °C

4: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 24 h / 20 °C / 750.08 Torr

5: sodium hydroxide / isopropyl alcohol; water / 72 h / 20 °C

With sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; hydrogen; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; palladium 10% on activated carbon; In tetrahydrofuran; 1,4-dioxane; methanol; water; N,N-dimethyl-formamide; isopropyl alcohol; tert-butyl alcohol;