2-Aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine

Base Information

Chemical Name:2-Aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine
CAS No.:112887-45-3
Molecular Formula:C₁₄H₂₁ClN₂O₂
Molecular Weight:284.786
Hs Code.:
DSSTox Substance ID:DTXSID601216557

Synonyms:SCHEMBL7374116;DWXFDGVDGNNQBO-UHFFFAOYSA-N;DTXSID601216557;112887-45-3;2-aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine;4-[3-(4-Chlorophenoxy)propyl]-2-morpholinemethanamine

Suppliers and Price of 2-Aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:284.1291556
Heavy Atom Count:19
Complexity:248

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COC(CN1CCCOC2=CC=C(C=C2)Cl)CN

Technology Process of 2-Aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine

There total 4 articles about 2-Aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 112887-55-5
2-acetylaminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine

: 112887-45-3
2-aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine

Guidance literature:: With sodium hydroxide; for 20h; Heating;
DOI:10.1248/cpb.40.652

Reference yield:

: 112913-96-9
2-(N-acetylaminomethyl)-4-benzylmorpholine

: 112887-45-3
2-aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / 10percent Pd/C / ethanol; acetic acid / 60 °C

2: K₂CO₃, KI / butan-2-one / 17 h / Heating

3: 10percent NaOH / 20 h / Heating

With sodium hydroxide; hydrogen; potassium carbonate; potassium iodide; palladium on activated charcoal; In ethanol; acetic acid; butanone;
DOI:10.1248/cpb.40.652

Reference yield:

: 64473-35-4
3-(4-chlorophenyl)propyl bromide

: 112887-45-3
2-aminomethyl-4-[3-(4-chlorophenoxy)propyl]morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃, KI / butan-2-one / 17 h / Heating

2: 10percent NaOH / 20 h / Heating

With sodium hydroxide; potassium carbonate; potassium iodide; In butanone;
DOI:10.1248/cpb.40.652